Cargando…

Opioid withdrawal delirium without convulsions: A Rare Case report

INTRODUCTION: Opioid withdrawal symptoms classically include severe muscle cramps, bone aches, autonomic symptoms, anxiety. Patients seldom have other complications like delirium and convulsions unless they have comorbid medical illnesses. OBJECTIVES: We hereby report a case of opioid withdrawal del...

Descripción completa

Detalles Bibliográficos
Autores principales: Singh, D.S., Paul, S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568023/
http://dx.doi.org/10.1192/j.eurpsy.2022.2144
_version_ 1784809545342648320
author Singh, D.S.
Paul, S.
author_facet Singh, D.S.
Paul, S.
author_sort Singh, D.S.
collection PubMed
description INTRODUCTION: Opioid withdrawal symptoms classically include severe muscle cramps, bone aches, autonomic symptoms, anxiety. Patients seldom have other complications like delirium and convulsions unless they have comorbid medical illnesses. OBJECTIVES: We hereby report a case of opioid withdrawal delirium. METHODS: A 20-year-old man with dependence for opiods and nicotine was admitted after compete history and mental status and physical examination, last intake for both substances 2 days back. There was no history of fever, head injury, siezures and other substance use. All investigations done were normal and urine drug screen was negative for other substances. Treatment was started with clonidine and quetiapine for sleep and Nsaids on prn basis. After 2 days there was hallucinatory behaviour, agitation, fleeting episodes of recognising family members, hearing voices and decreased sleep observed. Patient required sedation with 10 mg of lorazepam and haloperidol before he went to sleep.Later on lorazepam 8 mg in divided doses and clonidine was tapered off gradually and patient as discharged on naltrexone 50mg. RESULTS: In our case we could not find any other reason for delirium.These complications are rare feature of delirium, parker et all reported 5 such cases. One of limitations was we didnt do blood alcohol levels which could have ruled out alcohol use. CONCLUSIONS: This case is unique in terms of presenting with delirium without convulsions after 4 days of abstinence. No associated comorbidities, organic causes, and other substance use in dependence pattern or recently used. Use of a street variety (mixed with impurities) could be a risk factor for delirium in our patient.Psychiatrist need to be aware of complication. DISCLOSURE: No significant relationships.
format Online
Article
Text
id pubmed-9568023
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cambridge University Press
record_format MEDLINE/PubMed
spelling pubmed-95680232022-10-17 Opioid withdrawal delirium without convulsions: A Rare Case report Singh, D.S. Paul, S. Eur Psychiatry Abstract INTRODUCTION: Opioid withdrawal symptoms classically include severe muscle cramps, bone aches, autonomic symptoms, anxiety. Patients seldom have other complications like delirium and convulsions unless they have comorbid medical illnesses. OBJECTIVES: We hereby report a case of opioid withdrawal delirium. METHODS: A 20-year-old man with dependence for opiods and nicotine was admitted after compete history and mental status and physical examination, last intake for both substances 2 days back. There was no history of fever, head injury, siezures and other substance use. All investigations done were normal and urine drug screen was negative for other substances. Treatment was started with clonidine and quetiapine for sleep and Nsaids on prn basis. After 2 days there was hallucinatory behaviour, agitation, fleeting episodes of recognising family members, hearing voices and decreased sleep observed. Patient required sedation with 10 mg of lorazepam and haloperidol before he went to sleep.Later on lorazepam 8 mg in divided doses and clonidine was tapered off gradually and patient as discharged on naltrexone 50mg. RESULTS: In our case we could not find any other reason for delirium.These complications are rare feature of delirium, parker et all reported 5 such cases. One of limitations was we didnt do blood alcohol levels which could have ruled out alcohol use. CONCLUSIONS: This case is unique in terms of presenting with delirium without convulsions after 4 days of abstinence. No associated comorbidities, organic causes, and other substance use in dependence pattern or recently used. Use of a street variety (mixed with impurities) could be a risk factor for delirium in our patient.Psychiatrist need to be aware of complication. DISCLOSURE: No significant relationships. Cambridge University Press 2022-09-01 /pmc/articles/PMC9568023/ http://dx.doi.org/10.1192/j.eurpsy.2022.2144 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Abstract
Singh, D.S.
Paul, S.
Opioid withdrawal delirium without convulsions: A Rare Case report
title Opioid withdrawal delirium without convulsions: A Rare Case report
title_full Opioid withdrawal delirium without convulsions: A Rare Case report
title_fullStr Opioid withdrawal delirium without convulsions: A Rare Case report
title_full_unstemmed Opioid withdrawal delirium without convulsions: A Rare Case report
title_short Opioid withdrawal delirium without convulsions: A Rare Case report
title_sort opioid withdrawal delirium without convulsions: a rare case report
topic Abstract
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568023/
http://dx.doi.org/10.1192/j.eurpsy.2022.2144
work_keys_str_mv AT singhds opioidwithdrawaldeliriumwithoutconvulsionsararecasereport
AT pauls opioidwithdrawaldeliriumwithoutconvulsionsararecasereport