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Electrophysiological characterization of schizophrenia-associated variants in NaV1.2 sodium channel

INTRODUCTION: A major pathophysiological hypothesis of schizophrenia states an increased activity of glutamatergic neurons leading to an imbalance of neural excitation and inhibition (E/I-imbalance). One potential molecular mechanism of E/I-imbalance is a dysfunction of voltage-gated sodium channels...

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Detalles Bibliográficos
Autores principales:	Suslova, M., Hautvast, P., Gaebler, A., Lampert, A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cambridge University Press 2022
Materias:	Abstract
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568033/ http://dx.doi.org/10.1192/j.eurpsy.2022.1967

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