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Childbirth hospitalizations in Bipolar disorder patients: a nationwide study protocol
INTRODUCTION: Bipolar disorder (BD) is usually diagnosed in adulthood, around childbearing age. Research has shown that BD has deleterious effects on pregnant women and birth outcomes. However, few nationwide studies using administrative data have approached this at-risk population focusing specific...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cambridge University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568158/ http://dx.doi.org/10.1192/j.eurpsy.2022.1958 |
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author | Araújo, G. Gonçalves-Pinho, M. Ferreira, A.R. Fernandes, L. Freitas, A. |
author_facet | Araújo, G. Gonçalves-Pinho, M. Ferreira, A.R. Fernandes, L. Freitas, A. |
author_sort | Araújo, G. |
collection | PubMed |
description | INTRODUCTION: Bipolar disorder (BD) is usually diagnosed in adulthood, around childbearing age. Research has shown that BD has deleterious effects on pregnant women and birth outcomes. However, few nationwide studies using administrative data have approached this at-risk population focusing specifically on childbirth. OBJECTIVES: This study aims to characterize hospitalizations of women with BD in the peripartum period regarding sociodemographic and clinical variables and to investigate the impact BD has on hospitalization outcomes. METHODS: An observational retrospective study will be performed using an administrative database that comprises routinely collected hospitalization data from all mainland Portuguese public hospitals. International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes will be used to identify all women’s admissions for childbirth purposes (V27.X) and codes 296.XX (except 296.2X, 296.3X, 296.9X) will be used to ascertain BD. Episodes will be assigned to one of two mutually exclusive groups (with vs without BD). Multivariate methods will be used to compare both groups concerning key variables and outcomes. This work will comply with the RECORD statement recommendations. RESULTS: Descriptive and analytical statistics will be conducted in order to describe and characterize this group of patients. Results will be presented as crude and adjusted odds ratio quantifying the risk associated with BD in pregnancy, childbirth and hospitalization outcomes. Findings will be disseminated via publication in peer-reviewed journals. CONCLUSIONS: With this nationwide analysis, we expect to contribute to a better understanding of the demographic and clinical profile of pregnant women with BD and to encourage timely medical and psychological interventions during gestation and childbirth. DISCLOSURE: No significant relationships. |
format | Online Article Text |
id | pubmed-9568158 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cambridge University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-95681582022-10-17 Childbirth hospitalizations in Bipolar disorder patients: a nationwide study protocol Araújo, G. Gonçalves-Pinho, M. Ferreira, A.R. Fernandes, L. Freitas, A. Eur Psychiatry Abstract INTRODUCTION: Bipolar disorder (BD) is usually diagnosed in adulthood, around childbearing age. Research has shown that BD has deleterious effects on pregnant women and birth outcomes. However, few nationwide studies using administrative data have approached this at-risk population focusing specifically on childbirth. OBJECTIVES: This study aims to characterize hospitalizations of women with BD in the peripartum period regarding sociodemographic and clinical variables and to investigate the impact BD has on hospitalization outcomes. METHODS: An observational retrospective study will be performed using an administrative database that comprises routinely collected hospitalization data from all mainland Portuguese public hospitals. International Classification of Diseases, Ninth Revision, Clinical Modification (ICD-9-CM) codes will be used to identify all women’s admissions for childbirth purposes (V27.X) and codes 296.XX (except 296.2X, 296.3X, 296.9X) will be used to ascertain BD. Episodes will be assigned to one of two mutually exclusive groups (with vs without BD). Multivariate methods will be used to compare both groups concerning key variables and outcomes. This work will comply with the RECORD statement recommendations. RESULTS: Descriptive and analytical statistics will be conducted in order to describe and characterize this group of patients. Results will be presented as crude and adjusted odds ratio quantifying the risk associated with BD in pregnancy, childbirth and hospitalization outcomes. Findings will be disseminated via publication in peer-reviewed journals. CONCLUSIONS: With this nationwide analysis, we expect to contribute to a better understanding of the demographic and clinical profile of pregnant women with BD and to encourage timely medical and psychological interventions during gestation and childbirth. DISCLOSURE: No significant relationships. Cambridge University Press 2022-09-01 /pmc/articles/PMC9568158/ http://dx.doi.org/10.1192/j.eurpsy.2022.1958 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Abstract Araújo, G. Gonçalves-Pinho, M. Ferreira, A.R. Fernandes, L. Freitas, A. Childbirth hospitalizations in Bipolar disorder patients: a nationwide study protocol |
title | Childbirth hospitalizations in Bipolar disorder patients: a nationwide study protocol |
title_full | Childbirth hospitalizations in Bipolar disorder patients: a nationwide study protocol |
title_fullStr | Childbirth hospitalizations in Bipolar disorder patients: a nationwide study protocol |
title_full_unstemmed | Childbirth hospitalizations in Bipolar disorder patients: a nationwide study protocol |
title_short | Childbirth hospitalizations in Bipolar disorder patients: a nationwide study protocol |
title_sort | childbirth hospitalizations in bipolar disorder patients: a nationwide study protocol |
topic | Abstract |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568158/ http://dx.doi.org/10.1192/j.eurpsy.2022.1958 |
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