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O-Glycoproteomic analysis of engineered heavily glycosylated fusion proteins using nanoHILIC-MS

Recombinant protein engineering design affects therapeutic properties including protein efficacy, safety, and immunogenicity. Importantly, glycosylation modulates glycoprotein therapeutic pharmacokinetics, pharmacodynamics, and effector functions. Furthermore, the development of fusion proteins requ...

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Detalles Bibliográficos
Autores principales:	Cavallero, Gustavo J., Wang, Yan, Nwosu, Charles, Gu, Sheng, Meiyappan, Muthuraman, Zaia, Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568489/ https://www.ncbi.nlm.nih.gov/pubmed/36136114 http://dx.doi.org/10.1007/s00216-022-04318-7

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