Cargando…

O-Glycoproteomic analysis of engineered heavily glycosylated fusion proteins using nanoHILIC-MS

Recombinant protein engineering design affects therapeutic properties including protein efficacy, safety, and immunogenicity. Importantly, glycosylation modulates glycoprotein therapeutic pharmacokinetics, pharmacodynamics, and effector functions. Furthermore, the development of fusion proteins requ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cavallero, Gustavo J., Wang, Yan, Nwosu, Charles, Gu, Sheng, Meiyappan, Muthuraman, Zaia, Joseph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568489/ https://www.ncbi.nlm.nih.gov/pubmed/36136114 http://dx.doi.org/10.1007/s00216-022-04318-7

Ejemplares similares

Characterization of Nucleosides and Nucleobases in Natural Cordyceps by HILIC–ESI/TOF/MS and HILIC–ESI/MS
por: Zhao, Heng-Qiang, et al.
Publicado: (2013)

Shape-anisotropic enhanced damping in CoZr periodic arrays of nanohill structure
por: Wang, Fenglong, et al.
Publicado: (2013)

Glycoproteomics: Identifying the Glycosylation of Prostate Specific Antigen at Normal and High Isoelectric Points by LC–MS/MS
por: Song, Ehwang, et al.
Publicado: (2014)

Development of a rapid profiling method for the analysis of polar analytes in urine using HILIC–MS and ion mobility enabled HILIC–MS
por: King, Adam M., et al.
Publicado: (2019)

Targeted glycoproteomic identification of cancer cell glycosylation
por: Powlesland, Alex S, et al.
Publicado: (2009)

Integrative glycoproteomics reveals protein N-glycosylation aberrations and glycoproteomic network alterations in Alzheimer’s disease
por: Zhang, Qi, et al.
Publicado: (2020)

Sequential Analysis of the N/O-Glycosylation of Heavily Glycosylated HIV-1 gp120 Using EThcD-sceHCD-MS/MS
por: Zhang, Yong, et al.
Publicado: (2021)

HILIC-MS for Untargeted Profiling of the Free Glycation Product Diversity
por: Yan, Yingfei, et al.
Publicado: (2022)

N-glycoproteome Analysis of the Secretome of Human Metastatic Hepatocellular Carcinoma Cell Lines Combining Hydrazide Chemistry, HILIC Enrichment and Mass Spectrometry
por: Li, Xianyu, et al.
Publicado: (2013)

Precision Glycoproteomics Reveals Distinctive N-Glycosylation in Human Spermatozoa
por: Xin, Miaomiao, et al.
Publicado: (2022)

Multiple Layers of Complexity in O-Glycosylation Illustrated With the Urinary Glycoproteome
por: Pap, Adam, et al.
Publicado: (2022)

Glycoproteomics in Cerebrospinal Fluid Reveals Brain-Specific Glycosylation Changes
por: Baerenfaenger, Melissa, et al.
Publicado: (2023)

Glycoproteomics-Compatible MS/MS-Based Quantification of Glycopeptide Isomers
por: Maliepaard, Joshua C.L., et al.
Publicado: (2023)

The Need for Community Standards to Enable Accurate Comparison of Glycoproteomics Algorithm Performance
por: Hackett, William E., et al.
Publicado: (2021)

Capillary HILIC-MS: A New Tool for Sensitive Top-Down Proteomics
por: Gargano, Andrea F.G., et al.
Publicado: (2018)

Development and Optimisation of HILIC-LC-MS Method for Determination of Carbohydrates in Fermentation Samples
por: Pismennõi, Dmitri, et al.
Publicado: (2021)

Comprehensive glycoproteomics shines new light on the complexity and extent of glycosylation in archaea
por: Schulze, Stefan, et al.
Publicado: (2021)

Roles of glycosylation at the cancer cell surface: opportunities for large scale glycoproteomics
por: Čaval, Tomislav, et al.
Publicado: (2023)

Direct injection HILIC–MS/MS analysis of darunavir in rat plasma applying supported liquid extraction
por: Ramesh, Bokka, et al.
Publicado: (2015)

Sample Preparation Strategies for the Effective Quantitation of Hydrophilic Metabolites in Serum by Multi-Targeted HILIC-MS/MS
por: Tsakelidou, Elisavet, et al.
Publicado: (2017)

Development and validation of an HILIC–MS/MS method by one-step precipitation for chloroquine in miniature pig plasma
por: Wang, Zhan-Zhang, et al.
Publicado: (2016)

Simultaneous quantitation of multiple myeloma related dietary metabolites in serum using HILIC-LC-MS/MS
por: Wang, Mo, et al.
Publicado: (2023)

Targeting Glycans and Heavily Glycosylated Proteins for Tumor Imaging
por: Houvast, Ruben D., et al.
Publicado: (2020)

Glycan Conformation in the Heavily Glycosylated Protein, CEACAM1
por: Rogals, Monique J., et al.
Publicado: (2022)

Biomarker Profiling for Pyridoxine Dependent Epilepsy in Dried Blood Spots by HILIC-ESI-MS
por: Mathew, Elizabeth Mary, et al.
Publicado: (2018)

HILIC-MS Rat Brain Analysis, A New Approach for the Study of Ischemic Attack
por: Miękus, Natalia, et al.
Publicado: (2017)

An Improved HILIC HPLC-MS/MS Method for the Determination of β-ODAP and Its α Isomer in Lathyrus sativus
por: Bento-Silva, Andreia, et al.
Publicado: (2019)

Validation of a HILIC UHPLC-MS/MS Method for Amino Acid Profiling in Triticum Species Wheat Flours
por: Tsochatzis, Emmanouil, et al.
Publicado: (2019)

Simultaneous Determination of Methylated Nucleosides by HILIC–MS/MS Revealed Their Alterations in Urine from Breast Cancer Patients
por: Fang, Zhihao, et al.
Publicado: (2022)

Global analysis of the glycoproteome in Saccharomyces cerevisiae reveals new roles for protein glycosylation in eukaryotes
por: Kung, Li A, et al.
Publicado: (2009)

Glycoproteomics revealed novel N-glycosylation biomarkers for early diagnosis of lung adenocarcinoma cancers
por: Fang, Kai, et al.
Publicado: (2022)

The S-Layer Protein of the Anammox Bacterium Kuenenia stuttgartiensis Is Heavily O-Glycosylated
por: van Teeseling, Muriel C. F., et al.
Publicado: (2016)

Automatic Supported Liquid Extraction (SLE) Coupled with HILIC-MS/MS: An Application to Method Development and Validation of Erlotinib in Human Plasma
por: Pan, Jiongwei, et al.
Publicado: (2010)

Single-Step Extraction Coupled with Targeted HILIC-MS/MS Approach for Comprehensive Analysis of Human Plasma Lipidome and Polar Metabolome
por: Medina, Jessica, et al.
Publicado: (2020)

Nascent Glycoproteome Reveals That N-Linked Glycosylation Inhibitor-1 Suppresses Expression of Glycosylated Lysosome-Associated Membrane Protein-2
por: Cao, Xinyi, et al.
Publicado: (2022)

Comprehensive Plasma N-Glycoproteome Profiling Based on EThcD-sceHCD-MS/MS
por: Mao, Yonghong, et al.
Publicado: (2022)

In-Depth Matrisome and Glycoproteomic Analysis of Human Brain Glioblastoma Versus Control Tissue
por: Sethi, Manveen K., et al.
Publicado: (2022)

Comprehensive and simultaneous coverage of lipid and polar metabolites for endogenous cellular metabolomics using HILIC-TOF-MS
por: Fei, Fan, et al.
Publicado: (2014)

HILIC–MRM–MS for Linkage-Specific Separation of Sialylated Glycopeptides to Quantify Prostate-Specific Antigen Proteoforms
por: van der Burgt, Yuri E. M., et al.
Publicado: (2020)

Quantitative Glycoproteomics Analysis Reveals Changes in N-Glycosylation Level Associated with Pancreatic Ductal Adenocarcinoma
por: Pan, Sheng, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_3sneumk2s8c55no7hulkjk3hh7