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Phosphatase protector alpha4 (α4) is involved in adipocyte maintenance and mitochondrial homeostasis through regulation of insulin signaling
Insulin signaling is mediated via a network of protein phosphorylation. Dysregulation of this network is central to obesity, type 2 diabetes and metabolic syndrome. Here we investigate the role of phosphatase binding protein Alpha4 (α4) that is essential for the serine/threonine protein phosphatase...
Autores principales: | Sakaguchi, Masaji, Okagawa, Shota, Okubo, Yuma, Otsuka, Yuri, Fukuda, Kazuki, Igata, Motoyuki, Kondo, Tatsuya, Sato, Yoshifumi, Yoshizawa, Tatsuya, Fukuda, Takaichi, Yamagata, Kazuya, Cai, Weikang, Tseng, Yu-Hua, Sakaguchi, Nobuo, Kahn, C. Ronald, Araki, Eiichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568526/ https://www.ncbi.nlm.nih.gov/pubmed/36241662 http://dx.doi.org/10.1038/s41467-022-33842-4 |
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