TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis

The fatty acid composition of phosphatidylethanolamine (PE) determines cellular metabolism, oxidative stress, and inflammation. However, our understanding of how cells regulate PE composition is limited. Here, we identify a genetic locus on mouse chromosome 11, containing two poorly characterized ge...

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Detalles Bibliográficos
Autores principales: Petkevicius, Kasparas, Palmgren, Henrik, Glover, Matthew S., Ahnmark, Andrea, Andréasson, Anne-Christine, Madeyski-Bengtson, Katja, Kawana, Hiroki, Allman, Erik L., Kaper, Delaney, Uhrbom, Martin, Andersson, Liselotte, Aasehaug, Leif, Forsström, Johan, Wallin, Simonetta, Ahlstedt, Ingela, Leke, Renata, Karlsson, Daniel, González-King, Hernán, Löfgren, Lars, Nilsson, Ralf, Pellegrini, Giovanni, Kono, Nozomu, Aoki, Junken, Hess, Sonja, Sienski, Grzegorz, Pilon, Marc, Bohlooly-Y, Mohammad, Maresca, Marcello, Peng, Xiao-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568529/
https://www.ncbi.nlm.nih.gov/pubmed/36241646
http://dx.doi.org/10.1038/s41467-022-33735-6

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