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Massive expansion of multiple clones in the mouse hematopoietic system long after whole-body X-irradiation

Clonal hematopoiesis (CH) is prevalent in the elderly and associates with hematologic malignancy and cardiovascular disease. Although the risk of developing these diseases increases with radiation doses in atomic-bomb survivors, the causal relationship between radiation exposure and CH is unclear. T...

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Detalles Bibliográficos
Autores principales: Yoshida, Kengo, Satoh, Yasunari, Uchimura, Arikuni, Misumi, Munechika, Kyoizumi, Seishi, Taga, Masataka, Matsuda, Yukiko, Noda, Asao, Kusunoki, Yoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568546/
https://www.ncbi.nlm.nih.gov/pubmed/36241679
http://dx.doi.org/10.1038/s41598-022-21621-6