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Massive expansion of multiple clones in the mouse hematopoietic system long after whole-body X-irradiation
Clonal hematopoiesis (CH) is prevalent in the elderly and associates with hematologic malignancy and cardiovascular disease. Although the risk of developing these diseases increases with radiation doses in atomic-bomb survivors, the causal relationship between radiation exposure and CH is unclear. T...
Autores principales: | Yoshida, Kengo, Satoh, Yasunari, Uchimura, Arikuni, Misumi, Munechika, Kyoizumi, Seishi, Taga, Masataka, Matsuda, Yukiko, Noda, Asao, Kusunoki, Yoichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568546/ https://www.ncbi.nlm.nih.gov/pubmed/36241679 http://dx.doi.org/10.1038/s41598-022-21621-6 |
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