A proliferative subtype of colorectal liver metastases exhibits hypersensitivity to cytotoxic chemotherapy

Personalized treatment approaches for patients with limited liver metastases from colorectal cancer are critically needed. By leveraging three large, independent cohorts of patients with colorectal liver metastases (n = 336), we found that a proliferative subtype associated with elevated CIN70 score...

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Detalles Bibliográficos
Autores principales: Spurr, Liam F., Martinez, Carlos A., Katipally, Rohan R., Iyer, Soumya C., Pugh, Sian A., Bridgewater, John A., Primrose, John N., Domingo, Enric, Maughan, Timothy S., D’Angelica, Michael I., Talamonti, Mark, Posner, Mitchell C., Connell, Philip P., Weichselbaum, Ralph R., Pitroda, Sean P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568565/
https://www.ncbi.nlm.nih.gov/pubmed/36241710
http://dx.doi.org/10.1038/s41698-022-00318-z

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