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Fibrocytes boost tumor-supportive phenotypic switches in the lung cancer niche via the endothelin system
Fibrocytes are bone marrow–derived monocytic cells implicated in wound healing. Here, we identify their role in lung cancer progression/ metastasis. Selective manipulation of fibrocytes in mouse lung tumor models documents the central role of fibrocytes in boosting niche features and enhancing metas...
Autores principales: | Weigert, Andreas, Zheng, Xiang, Nenzel, Alina, Turkowski, Kati, Günther, Stefan, Strack, Elisabeth, Sirait-Fischer, Evelyn, Elwakeel, Eiman, Kur, Ivan M., Nikam, Vandana S., Valasarajan, Chanil, Winter, Hauke, Wissgott, Alexander, Voswinkel, Robert, Grimminger, Friedrich, Brüne, Bernhard, Seeger, Werner, Pullamsetti, Soni Savai, Savai, Rajkumar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568595/ https://www.ncbi.nlm.nih.gov/pubmed/36241617 http://dx.doi.org/10.1038/s41467-022-33458-8 |
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