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Expression and regulation of recently discovered hyaluronidases, HYBID and TMEM2, in chondrocytes from knee osteoarthritic cartilage
Destruction of articular cartilage in osteoarthritis (OA) is initiated by depletion of the hyaluronan (HA)-aggrecan network, followed by degradation of the collagen fibrils. Previously, we reported the implications of HA-binding protein involved in HA depolymerization (HYBID), alias cell migration-i...
Autores principales: | Shiozawa, Jun, de Vega, Susana, Yoshinaga, Chiho, Ji, Xang, Negishi, Yoshifumi, Momoeda, Masahiro, Nakamura, Tomomi, Yoshida, Hiroyuki, Kaneko, Haruka, Ishijima, Muneaki, Okada, Yasunori |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568606/ https://www.ncbi.nlm.nih.gov/pubmed/36241903 http://dx.doi.org/10.1038/s41598-022-22230-z |
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