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Expression and regulation of recently discovered hyaluronidases, HYBID and TMEM2, in chondrocytes from knee osteoarthritic cartilage

Destruction of articular cartilage in osteoarthritis (OA) is initiated by depletion of the hyaluronan (HA)-aggrecan network, followed by degradation of the collagen fibrils. Previously, we reported the implications of HA-binding protein involved in HA depolymerization (HYBID), alias cell migration-i...

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Detalles Bibliográficos
Autores principales: Shiozawa, Jun, de Vega, Susana, Yoshinaga, Chiho, Ji, Xang, Negishi, Yoshifumi, Momoeda, Masahiro, Nakamura, Tomomi, Yoshida, Hiroyuki, Kaneko, Haruka, Ishijima, Muneaki, Okada, Yasunori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568606/
https://www.ncbi.nlm.nih.gov/pubmed/36241903
http://dx.doi.org/10.1038/s41598-022-22230-z

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