A pregnancy with nephrotic syndrome: A rare case

INTRODUCTION: Systemic lupus erythematosus (SLE) found during pregnancy is often flared SLE. CASE PRESENTATION: This study reported a 23-year-old woman diagnosed with nephrotic syndrome with an 18/19-week pregnancy. The cause of nephrotic syndrome must be established by ruling out all possible secondary causes, especially in pregnancy with preeclampsia which can also occur with proteinuria. In lupus nephritis, renal biopsy as the standard gold examination plays a role in determining further management and the prognosis of the patient's future renal function. A kidney biopsy is recommended if the urinary protein excretion exceeds 500 mg/24 h with the aim of early detection and treatment to prevent long-term complications to the kidneys. DISCUSSION: Management of nephrotic syndrome in pregnancy used corticosteroid and immunosuppressive. CONCLUSION: Pregnancy prognosis in women with active SLE is generally poor, with a high risk of miscarriage.