Malaria parasites utilize two essential plasma membrane fusogens for gamete fertilization

Cell fusion of female and male gametes is the climax of sexual reproduction. In many organisms, the Hapless 2 (HAP2) family of proteins play a critical role in gamete fusion. We find that Plasmodium falciparum, the causative agent of human malaria, expresses two HAP2 proteins: PfHAP2 and PfHAP2p. Th...

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Detalles Bibliográficos
Autores principales: Kumar, Sudhir, Valansi, Clari, Haile, Meseret T., Li, Xiaohui, Flyak, Kateryna, Dwivedy, Abhisek, Abatiyow, Biley A., Leeb, Amanda S., Kennedy, Spencer Y., Camargo, Nelly M., Vaughan, Ashley M., Brukman, Nicolas G., Podbilewicz, Benjamin, Kappe, Stefan H. I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568910/
https://www.ncbi.nlm.nih.gov/pubmed/36241929
http://dx.doi.org/10.1007/s00018-022-04583-w

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