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Highly efficient and durable antimicrobial nanocomposite textiles

Healthcare associated infections cause millions of hospitalizations and cost billions of dollars every year. A potential solution to address this problem is to develop antimicrobial textile for healthcare fabrics (hospital bedding, gowns, lab coats, etc.). Metal nanoparticle-coated textile has been...

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Autores principales: Novi, Vinni Thekkudan, Gonzalez, Andrew, Brockgreitens, John, Abbas, Abdennour
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568944/
https://www.ncbi.nlm.nih.gov/pubmed/36243757
http://dx.doi.org/10.1038/s41598-022-22370-2
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author Novi, Vinni Thekkudan
Gonzalez, Andrew
Brockgreitens, John
Abbas, Abdennour
author_facet Novi, Vinni Thekkudan
Gonzalez, Andrew
Brockgreitens, John
Abbas, Abdennour
author_sort Novi, Vinni Thekkudan
collection PubMed
description Healthcare associated infections cause millions of hospitalizations and cost billions of dollars every year. A potential solution to address this problem is to develop antimicrobial textile for healthcare fabrics (hospital bedding, gowns, lab coats, etc.). Metal nanoparticle-coated textile has been proven to possess antimicrobial properties but have not been adopted by healthcare facilities due to risks of leaching and subsequent loss of function, toxicity, and environmental pollution. This work presents the development and testing of antimicrobial zinc nanocomposite textiles, fabricated using a novel Crescoating process. In this process, zinc nanoparticles are grown in situ within the bulk of different natural and synthetic fabrics to form safe and durable nanocomposites. The zinc nanocomposite textiles show unprecedented microbial reduction of 99.99% (4 log(10)) to 99.9999% (6 log(10)) within 24 h on the most common Gram-positive and Gram-negative bacteria, and fungal pathogens. Furthermore, the antimicrobial activity remains intact even after 100 laundry cycles, demonstrating the high longevity and durability of the textile. Independent dermatological evaluation confirmed that the novel textile is non-irritating and hypoallergenic.
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spelling pubmed-95689442022-10-16 Highly efficient and durable antimicrobial nanocomposite textiles Novi, Vinni Thekkudan Gonzalez, Andrew Brockgreitens, John Abbas, Abdennour Sci Rep Article Healthcare associated infections cause millions of hospitalizations and cost billions of dollars every year. A potential solution to address this problem is to develop antimicrobial textile for healthcare fabrics (hospital bedding, gowns, lab coats, etc.). Metal nanoparticle-coated textile has been proven to possess antimicrobial properties but have not been adopted by healthcare facilities due to risks of leaching and subsequent loss of function, toxicity, and environmental pollution. This work presents the development and testing of antimicrobial zinc nanocomposite textiles, fabricated using a novel Crescoating process. In this process, zinc nanoparticles are grown in situ within the bulk of different natural and synthetic fabrics to form safe and durable nanocomposites. The zinc nanocomposite textiles show unprecedented microbial reduction of 99.99% (4 log(10)) to 99.9999% (6 log(10)) within 24 h on the most common Gram-positive and Gram-negative bacteria, and fungal pathogens. Furthermore, the antimicrobial activity remains intact even after 100 laundry cycles, demonstrating the high longevity and durability of the textile. Independent dermatological evaluation confirmed that the novel textile is non-irritating and hypoallergenic. Nature Publishing Group UK 2022-10-15 /pmc/articles/PMC9568944/ /pubmed/36243757 http://dx.doi.org/10.1038/s41598-022-22370-2 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Novi, Vinni Thekkudan
Gonzalez, Andrew
Brockgreitens, John
Abbas, Abdennour
Highly efficient and durable antimicrobial nanocomposite textiles
title Highly efficient and durable antimicrobial nanocomposite textiles
title_full Highly efficient and durable antimicrobial nanocomposite textiles
title_fullStr Highly efficient and durable antimicrobial nanocomposite textiles
title_full_unstemmed Highly efficient and durable antimicrobial nanocomposite textiles
title_short Highly efficient and durable antimicrobial nanocomposite textiles
title_sort highly efficient and durable antimicrobial nanocomposite textiles
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568944/
https://www.ncbi.nlm.nih.gov/pubmed/36243757
http://dx.doi.org/10.1038/s41598-022-22370-2
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