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Self-restricted circular RNA circSOX2 suppressed the malignant progression in SOX2-amplified LUSC

Lung squamous cell carcinoma (LUSC) is a histological subtype of non-small cell lung cancer with the worse progression. SRY-Box Transcription Factor 2 (SOX2) copy number amplification (CNA) is the oncogenic driver in ~60% of patients diagnosed with LUSC. Thus, SOX2 represents an effective therapeuti...

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Detalles Bibliográficos
Autores principales:	Liang, Yingkuan, Wang, Nan, Zhang, Yijian, Jiang, Wei, Fang, Chen, Feng, Yu, Ma, Haitao, Jiang, Feng, Dong, Gaochao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9568965/ https://www.ncbi.nlm.nih.gov/pubmed/36243874 http://dx.doi.org/10.1038/s41419-022-05288-5

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