Generation of mitochondria-rich kidney organoids from expandable intermediate mesoderm progenitors reprogrammed from human urine cells under defined medium

BACKGROUND: The kidneys require vast amounts of mitochondria to provide ample energy to reabsorb nutrients and regulate electrolyte, fluid, and blood pressure homeostasis. The lack of the human model hinders the investigation of mitochondria homeostasis related to kidney physiology and disease. RESU...

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Detalles Bibliográficos
Autores principales: Yuan, Yapei, Chen, Huan, Ou, Sihua, Cai, Baomei, Zhang, Ruifang, Qin, Yue, Pan, Mengjie, Cao, Shangtao, Pei, Duanqing, Hou, Fan Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569036/
https://www.ncbi.nlm.nih.gov/pubmed/36243732
http://dx.doi.org/10.1186/s13578-022-00909-0

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