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Suboptimal blood pressure control and its associated factors among people living with diabetes mellitus in sub-Saharan Africa: a systematic review and meta-analysis

BACKGROUND: Suboptimal blood pressure control among people living with diabetes mellitus (DM) is one of the primary causes of cardiovascular complications and death in sub-Saharan Africa (SSA). However, there is a paucity of evidence on the prevalence and associated factors of suboptimal blood press...

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Autores principales: Akalu, Yonas, Yeshaw, Yigizie, Tesema, Getayeneh Antehunegn, Tiruneh, Sofonyas Abebaw, Teshale, Achamyeleh Birhanu, Angaw, Dessie Abebaw, Gebrie, Misganew, Dagnew, Baye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569048/
https://www.ncbi.nlm.nih.gov/pubmed/36243876
http://dx.doi.org/10.1186/s13643-022-02090-4
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author Akalu, Yonas
Yeshaw, Yigizie
Tesema, Getayeneh Antehunegn
Tiruneh, Sofonyas Abebaw
Teshale, Achamyeleh Birhanu
Angaw, Dessie Abebaw
Gebrie, Misganew
Dagnew, Baye
author_facet Akalu, Yonas
Yeshaw, Yigizie
Tesema, Getayeneh Antehunegn
Tiruneh, Sofonyas Abebaw
Teshale, Achamyeleh Birhanu
Angaw, Dessie Abebaw
Gebrie, Misganew
Dagnew, Baye
author_sort Akalu, Yonas
collection PubMed
description BACKGROUND: Suboptimal blood pressure control among people living with diabetes mellitus (DM) is one of the primary causes of cardiovascular complications and death in sub-Saharan Africa (SSA). However, there is a paucity of evidence on the prevalence and associated factors of suboptimal blood pressure control in SSA. Therefore, this review aimed to estimate its pooled prevalence and associated factors among people living with DM in SSA.  METHODS: We systematically searched PubMed, African Journals OnLine, HINARI, ScienceDirect, Google Scholar, and direct Google to access observational studies conducted in SSA. Microsoft Excel spreadsheet was used to extract the data, which was exported into STATA/MP version 16.0 for further analyses. Heterogeneity across studies was checked using Cochran’s Q test statistics and I(2) test, and small study effect was checked using Funnel plot symmetry and Egger’s statistical test at a 5% significant level. A random-effects model was used to estimate the pooled prevalence and associated factors of suboptimal blood pressure control at a 95% confidence interval (CI) and significance level of p < 0.05. RESULTS: Of the 7329 articles retrieved, 21 articles were eligible for the meta-analysis. After performing random-effects model, the pooled prevalence of suboptimal blood pressure control was 69.8% (95% CI: 63.43, 76.25%). Poor adherence to antihypertensive treatment (OR = 1.7; 95% CI: 1.03–2.80, I(2) = 0.0%, p = 0.531) and overweight (OR = 2.4, 95% CI: 1.57–3.68, I(2) = 0.00%, p = 0.47) were significantly associated with suboptimal blood pressure control. CONCLUSIONS: The prevalence of suboptimal blood pressure control among diabetic patients in SSA was high, and poor adherence to antihypertensive treatment and overweight were significantly associated with suboptimal blood pressure control. Hence, there is an urgent need for initiatives to improve and control hypertension, and preventive measures should concentrate on modifiable risk factors. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42020187901. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13643-022-02090-4.
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spelling pubmed-95690482022-10-16 Suboptimal blood pressure control and its associated factors among people living with diabetes mellitus in sub-Saharan Africa: a systematic review and meta-analysis Akalu, Yonas Yeshaw, Yigizie Tesema, Getayeneh Antehunegn Tiruneh, Sofonyas Abebaw Teshale, Achamyeleh Birhanu Angaw, Dessie Abebaw Gebrie, Misganew Dagnew, Baye Syst Rev Research BACKGROUND: Suboptimal blood pressure control among people living with diabetes mellitus (DM) is one of the primary causes of cardiovascular complications and death in sub-Saharan Africa (SSA). However, there is a paucity of evidence on the prevalence and associated factors of suboptimal blood pressure control in SSA. Therefore, this review aimed to estimate its pooled prevalence and associated factors among people living with DM in SSA.  METHODS: We systematically searched PubMed, African Journals OnLine, HINARI, ScienceDirect, Google Scholar, and direct Google to access observational studies conducted in SSA. Microsoft Excel spreadsheet was used to extract the data, which was exported into STATA/MP version 16.0 for further analyses. Heterogeneity across studies was checked using Cochran’s Q test statistics and I(2) test, and small study effect was checked using Funnel plot symmetry and Egger’s statistical test at a 5% significant level. A random-effects model was used to estimate the pooled prevalence and associated factors of suboptimal blood pressure control at a 95% confidence interval (CI) and significance level of p < 0.05. RESULTS: Of the 7329 articles retrieved, 21 articles were eligible for the meta-analysis. After performing random-effects model, the pooled prevalence of suboptimal blood pressure control was 69.8% (95% CI: 63.43, 76.25%). Poor adherence to antihypertensive treatment (OR = 1.7; 95% CI: 1.03–2.80, I(2) = 0.0%, p = 0.531) and overweight (OR = 2.4, 95% CI: 1.57–3.68, I(2) = 0.00%, p = 0.47) were significantly associated with suboptimal blood pressure control. CONCLUSIONS: The prevalence of suboptimal blood pressure control among diabetic patients in SSA was high, and poor adherence to antihypertensive treatment and overweight were significantly associated with suboptimal blood pressure control. Hence, there is an urgent need for initiatives to improve and control hypertension, and preventive measures should concentrate on modifiable risk factors. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42020187901. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s13643-022-02090-4. BioMed Central 2022-10-15 /pmc/articles/PMC9569048/ /pubmed/36243876 http://dx.doi.org/10.1186/s13643-022-02090-4 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Akalu, Yonas
Yeshaw, Yigizie
Tesema, Getayeneh Antehunegn
Tiruneh, Sofonyas Abebaw
Teshale, Achamyeleh Birhanu
Angaw, Dessie Abebaw
Gebrie, Misganew
Dagnew, Baye
Suboptimal blood pressure control and its associated factors among people living with diabetes mellitus in sub-Saharan Africa: a systematic review and meta-analysis
title Suboptimal blood pressure control and its associated factors among people living with diabetes mellitus in sub-Saharan Africa: a systematic review and meta-analysis
title_full Suboptimal blood pressure control and its associated factors among people living with diabetes mellitus in sub-Saharan Africa: a systematic review and meta-analysis
title_fullStr Suboptimal blood pressure control and its associated factors among people living with diabetes mellitus in sub-Saharan Africa: a systematic review and meta-analysis
title_full_unstemmed Suboptimal blood pressure control and its associated factors among people living with diabetes mellitus in sub-Saharan Africa: a systematic review and meta-analysis
title_short Suboptimal blood pressure control and its associated factors among people living with diabetes mellitus in sub-Saharan Africa: a systematic review and meta-analysis
title_sort suboptimal blood pressure control and its associated factors among people living with diabetes mellitus in sub-saharan africa: a systematic review and meta-analysis
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569048/
https://www.ncbi.nlm.nih.gov/pubmed/36243876
http://dx.doi.org/10.1186/s13643-022-02090-4
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