Genetic variants associated with psychiatric disorders are enriched at epigenetically active sites in lymphoid cells

Multiple psychiatric disorders have been associated with abnormalities in both the innate and adaptive immune systems. The role of these abnormalities in pathogenesis, and whether they are driven by psychiatric risk variants, remains unclear. We test for enrichment of GWAS variants associated with m...

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Detalles Bibliográficos
Autores principales: Lynall, Mary-Ellen, Soskic, Blagoje, Hayhurst, James, Schwartzentruber, Jeremy, Levey, Daniel F., Pathak, Gita A., Polimanti, Renato, Gelernter, Joel, Stein, Murray B., Trynka, Gosia, Clatworthy, Menna R., Bullmore, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569335/
https://www.ncbi.nlm.nih.gov/pubmed/36243721
http://dx.doi.org/10.1038/s41467-022-33885-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569335/
https://www.ncbi.nlm.nih.gov/pubmed/36243721
http://dx.doi.org/10.1038/s41467-022-33885-7

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