NOD2 Signaling Circuitry during Allergen Sensitization Does Not Worsen Experimental Neutrophilic Asthma but Promotes a Th2/Th17 Profile in Asthma Patients but Not Healthy Subjects

Nucleotide-binding oligomerization domain 2 (NOD2) recognizes pathogens associated with the development of asthma. Moreover, NOD2 adjuvants are used in vaccine design to boost immune responses. Muramyl di-peptide (MDP) is a NOD2 ligand, which is able to promote Th2/Th17 responses. Furthermore, polym...

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Detalles Bibliográficos
Autores principales: Bouté, Mélodie, Ait Yahia, Saliha, Fan, Ying, Alvarez-Simon, Daniel, Vorng, Han, Balsamelli, Joanne, Nanou, Julie, de Nadai, Patricia, Chenivesse, Cécile, Tsicopoulos, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569442/
https://www.ncbi.nlm.nih.gov/pubmed/36233196
http://dx.doi.org/10.3390/ijms231911894

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