Quantification of Farnesylated Progerin in Hutchinson-Gilford Progeria Patient Cells by Mass Spectrometry

Hutchinson-Gilford progeria syndrome (HGPS) is a rare fatal disorder characterized by premature aging and death at a median age of 14.5 years. The most common cause of HGPS (affecting circa 90% of patients) is a de novo heterozygous synonymous single-base substitution (c.1824C>T; p.G608G) in the...

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Detalles Bibliográficos
Autores principales: Camafeita, Emilio, Jorge, Inmaculada, Rivera-Torres, José, Andrés, Vicente, Vázquez, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569443/
https://www.ncbi.nlm.nih.gov/pubmed/36233036
http://dx.doi.org/10.3390/ijms231911733

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