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Highly Conserved Interaction Profiles between Clinically Relevant Mutants of the Cytomegalovirus CDK-like Kinase pUL97 and Human Cyclins: Functional Significance of Cyclin H

The complex host interaction network of human cytomegalovirus (HCMV) involves the regulatory protein kinase pUL97, which represents a viral cyclin-dependent kinase (CDK) ortholog. pUL97 interacts with the three human cyclin types T1, H, and B1, whereby the binding region of cyclin T1 and the pUL97 o...

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Detalles Bibliográficos
Autores principales: Schütz, Martin, Müller, Regina, Socher, Eileen, Wangen, Christina, Full, Florian, Wyler, Emanuel, Wong, Diana, Scherer, Myriam, Stamminger, Thomas, Chou, Sunwen, Rawlinson, William D., Hamilton, Stuart T., Sticht, Heinrich, Marschall, Manfred
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569496/
https://www.ncbi.nlm.nih.gov/pubmed/36233116
http://dx.doi.org/10.3390/ijms231911814