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Research Progress on Bacterial Membrane Vesicles and Antibiotic Resistance
As a result of antibiotic overuse, bacterial antibiotic resistance has become a severe threat to worldwide public health. The development of more effective antimicrobial therapies and alternative antibiotic strategies is urgently required. The role played by bacterial membrane vesicles (BMVs) in ant...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569563/ https://www.ncbi.nlm.nih.gov/pubmed/36232856 http://dx.doi.org/10.3390/ijms231911553 |
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author | Liu, Xiaofei Xiao, Jinyang Wang, Shuming Zhou, Jinxia Qin, Jiale Jia, Zhibo Wang, Yanfeng Wang, Zhigang Zhang, Yongmin Hao, Huifang |
author_facet | Liu, Xiaofei Xiao, Jinyang Wang, Shuming Zhou, Jinxia Qin, Jiale Jia, Zhibo Wang, Yanfeng Wang, Zhigang Zhang, Yongmin Hao, Huifang |
author_sort | Liu, Xiaofei |
collection | PubMed |
description | As a result of antibiotic overuse, bacterial antibiotic resistance has become a severe threat to worldwide public health. The development of more effective antimicrobial therapies and alternative antibiotic strategies is urgently required. The role played by bacterial membrane vesicles (BMVs) in antibiotic resistance has become a current focus of research. BMVs are nanoparticles derived from the membrane components of Gram-negative and Gram-positive bacteria and contain diverse components originating from the cell envelope and cytoplasm. Antibiotic stress stimulates the secretion of BMVs. BMVs promote and mediate antibiotic resistance by multiple mechanisms. BMVs have been investigated as conceptually new antibiotics and drug-delivery vehicles. In this article, we outline the research related to BMVs and antibiotic resistance as a reference for the intentional use of BMVs to combat antibiotic resistance. |
format | Online Article Text |
id | pubmed-9569563 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95695632022-10-17 Research Progress on Bacterial Membrane Vesicles and Antibiotic Resistance Liu, Xiaofei Xiao, Jinyang Wang, Shuming Zhou, Jinxia Qin, Jiale Jia, Zhibo Wang, Yanfeng Wang, Zhigang Zhang, Yongmin Hao, Huifang Int J Mol Sci Review As a result of antibiotic overuse, bacterial antibiotic resistance has become a severe threat to worldwide public health. The development of more effective antimicrobial therapies and alternative antibiotic strategies is urgently required. The role played by bacterial membrane vesicles (BMVs) in antibiotic resistance has become a current focus of research. BMVs are nanoparticles derived from the membrane components of Gram-negative and Gram-positive bacteria and contain diverse components originating from the cell envelope and cytoplasm. Antibiotic stress stimulates the secretion of BMVs. BMVs promote and mediate antibiotic resistance by multiple mechanisms. BMVs have been investigated as conceptually new antibiotics and drug-delivery vehicles. In this article, we outline the research related to BMVs and antibiotic resistance as a reference for the intentional use of BMVs to combat antibiotic resistance. MDPI 2022-09-30 /pmc/articles/PMC9569563/ /pubmed/36232856 http://dx.doi.org/10.3390/ijms231911553 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Liu, Xiaofei Xiao, Jinyang Wang, Shuming Zhou, Jinxia Qin, Jiale Jia, Zhibo Wang, Yanfeng Wang, Zhigang Zhang, Yongmin Hao, Huifang Research Progress on Bacterial Membrane Vesicles and Antibiotic Resistance |
title | Research Progress on Bacterial Membrane Vesicles and Antibiotic Resistance |
title_full | Research Progress on Bacterial Membrane Vesicles and Antibiotic Resistance |
title_fullStr | Research Progress on Bacterial Membrane Vesicles and Antibiotic Resistance |
title_full_unstemmed | Research Progress on Bacterial Membrane Vesicles and Antibiotic Resistance |
title_short | Research Progress on Bacterial Membrane Vesicles and Antibiotic Resistance |
title_sort | research progress on bacterial membrane vesicles and antibiotic resistance |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569563/ https://www.ncbi.nlm.nih.gov/pubmed/36232856 http://dx.doi.org/10.3390/ijms231911553 |
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