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Lactate-Lactylation Hands between Metabolic Reprogramming and Immunosuppression
Immune evasion and metabolic reprogramming are two fundamental hallmarks of cancer. Interestingly, lactate closely links them together. However, lactate has long been recognized as a metabolic waste product. Lactate and the acidification of the tumor microenvironment (TME) promote key carcinogenesis...
Autores principales: | Chen, Lihua, Huang, Lixiang, Gu, Yu, Cang, Wei, Sun, Pengming, Xiang, Yang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569569/ https://www.ncbi.nlm.nih.gov/pubmed/36233246 http://dx.doi.org/10.3390/ijms231911943 |
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