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Lactate-Lactylation Hands between Metabolic Reprogramming and Immunosuppression

Immune evasion and metabolic reprogramming are two fundamental hallmarks of cancer. Interestingly, lactate closely links them together. However, lactate has long been recognized as a metabolic waste product. Lactate and the acidification of the tumor microenvironment (TME) promote key carcinogenesis...

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Detalles Bibliográficos
Autores principales: Chen, Lihua, Huang, Lixiang, Gu, Yu, Cang, Wei, Sun, Pengming, Xiang, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569569/
https://www.ncbi.nlm.nih.gov/pubmed/36233246
http://dx.doi.org/10.3390/ijms231911943

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