RUNX1/CEBPA Mutation in Acute Myeloid Leukemia Promotes Hypermethylation and Indicates for Demethylation Therapy

Acute myeloid leukemia (AML) is a rapidly progressing heterogeneous disease with a high mortality rate, which is characterized by hyperproliferation of atypical immature myeloid cells. The number of AML patients is expected to increase in the near future, due to the old-age-associated nature of AML...

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Detalles Bibliográficos
Autores principales: Romanova, Ekaterina I., Zubritskiy, Anatoliy V., Lioznova, Anna V., Ogunleye, Adewale J., Golotin, Vasily A., Guts, Anna A., Lennartsson, Andreas, Demidov, Oleg N., Medvedeva, Yulia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569612/
https://www.ncbi.nlm.nih.gov/pubmed/36232714
http://dx.doi.org/10.3390/ijms231911413

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