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IDO1 Modulates the Sensitivity of Epithelial Ovarian Cancer Cells to Cisplatin through ROS/p53-Dependent Apoptosis

Indoleamine 2,3-dioxygenase 1 (IDO1) is a heme-containing dioxygenase that may play a part in chemoresistance in ovarian cancer. However, its role in cisplatin (DDP) resistance is unclear. Here, the expression level of IDO1 in tumors in platinum-resistant (n = 22) and -sensitive (n = 46) ovarian can...

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Detalles Bibliográficos
Autores principales:	Wang, Houmei, Luo, Yuanyuan, Ran, Rui, Li, Xinya, Ling, Hongjian, Wen, Fang, Yu, Tinghe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569641/ https://www.ncbi.nlm.nih.gov/pubmed/36233312 http://dx.doi.org/10.3390/ijms231912002

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