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Promyelocytic Leukemia Protein Potently Restricts Human Cytomegalovirus Infection in Endothelial Cells
PML nuclear bodies (PML-NBs) are dynamic macromolecular complexes that mediate intrinsic immunity against viruses of different families, including human cytomegalovirus (HCMV). Upon HCMV infection, PML-NBs target viral genomes entering the nucleus and restrict viral immediate–early gene expression b...
Autores principales: | Seitz, Sven, Heusel, Anna Theresa, Stamminger, Thomas, Scherer, Myriam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569661/ https://www.ncbi.nlm.nih.gov/pubmed/36233232 http://dx.doi.org/10.3390/ijms231911931 |
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