Cargando…

Dysregulation of miRISC Regulatory Network Promotes Hepatocellular Carcinoma by Targeting PI3K/Akt Signaling Pathway

Hepatocellular carcinoma (HCC) remains the third leading malignancy worldwide, causing high mortality in adults and children. The neuropathology-associated gene AEG-1 functions as a scaffold protein to correctly assemble the RNA-induced silencing complex (RISC) and optimize or increase its activity....

Descripción completa

Detalles Bibliográficos
Autores principales:	Kannan, Maheshkumar, Jayamohan, Sridharan, Moorthy, Rajesh Kannan, Chabattula, Siva Chander, Ganeshan, Mathan, Arockiam, Antony Joseph Velanganni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569668/ https://www.ncbi.nlm.nih.gov/pubmed/36232606 http://dx.doi.org/10.3390/ijms231911300

Ejemplares similares

AEG-1/miR-221 Axis Cooperatively Regulates the Progression of Hepatocellular Carcinoma by Targeting PTEN/PI3K/AKT Signaling Pathway
por: Kannan, Maheshkumar, et al.
Publicado: (2019)

Dysregulation of miR-375/AEG-1 Axis by Human Papillomavirus 16/18-E6/E7 Promotes Cellular Proliferation, Migration, and Invasion in Cervical Cancer
por: Jayamohan, Sridharan, et al.
Publicado: (2019)

Corrigendum: Dysregulation of miR-375/AEG-1 Axis by Human Papillomavirus 16/18-E6/E7 Promotes Cellular Proliferation, Migration, and Invasion in Cervical Cancer
por: Jayamohan, Sridharan, et al.
Publicado: (2021)

Intracytoplasmic Re-localization of miRISC Complexes
por: Akgül, Bünyamin, et al.
Publicado: (2018)

The Role of Dynamic miRISC During Neuronal Development
por: Nawalpuri, Bharti, et al.
Publicado: (2020)

Modulation of miRISC-Mediated Gene Silencing in Eukaryotes
por: Jungers, Courtney F., et al.
Publicado: (2022)

Roles of the Core Components of the Mammalian miRISC in Chromatin Biology
por: La Rocca, Gaspare, et al.
Publicado: (2022)

Knockdown of human telomerase reverse transcriptase induces apoptosis in cervical cancer cell line
por: Nagapoosanam, Anantha Lakshmi, et al.
Publicado: (2019)

miRISC recruits decapping factors to miRNA targets to enhance their degradation
por: Nishihara, Tadashi, et al.
Publicado: (2013)

E-cadherin Interacts With Posttranslationally-Modified AGO2 to Enhance miRISC Activity
por: Li, Jie-Ning, et al.
Publicado: (2021)

An alternative miRISC targets a cancer‐associated coding sequence mutation in FOXL2
por: Shin, Eunkyoung, et al.
Publicado: (2020)

Homeostatic scaling is driven by a translation-dependent degradation axis that recruits miRISC remodeling
por: Srinivasan, Balakumar, et al.
Publicado: (2021)

Mammalian GW220/TNGW1 is essential for the formation of GW/P bodies containing miRISC
por: Castilla-Llorente, Virginia, et al.
Publicado: (2012)

miRISC and the CCR4–NOT complex silence mRNA targets independently of 43S ribosomal scanning
por: Kuzuoğlu‐Öztürk, Duygu, et al.
Publicado: (2016)

HuR protein attenuates miRNA-mediated repression by promoting miRISC dissociation from the target RNA
por: Kundu, Pradipta, et al.
Publicado: (2012)

Does Lin28 Antagonize miRNA-Mediated Repression by Displacing miRISC from Target mRNAs?
por: Kallen, Amanda N., et al.
Publicado: (2012)

Functional Analysis of Neuronal MicroRNAs in Caenorhabditis elegans Dauer Formation by Combinational Genetics and Neuronal miRISC Immunoprecipitation
por: Than, Minh T., et al.
Publicado: (2013)

TEG-1 CD2BP2 controls miRNA levels by regulating miRISC stability in C. elegans and human cells
por: Wang, Chris, et al.
Publicado: (2017)

MiR-490-3p Silences CDK1 and Inhibits the Proliferation of Colon Cancer Through an LLPS-Dependent miRISC System
por: Qin, Da, et al.
Publicado: (2021)

Extracellular microRNAs in human circulation are associated with miRISC complexes that are accessible to anti-AGO2 antibody and can bind target mimic oligonucleotides
por: Geekiyanage, Hirosha, et al.
Publicado: (2020)

Identification of HIV-1 sequences targeted by the miRNA Induced silencing complex (miRISC) using Argonaute 2 cross-linking and immunoprecipitation (HITS-CLIP)
por: Eckenfelder, Agathe, et al.
Publicado: (2013)

Mutations in Conserved Residues of the C. elegans microRNA Argonaute ALG-1 Identify Separable Functions in ALG-1 miRISC Loading and Target Repression
por: Zinovyeva, Anna Y., et al.
Publicado: (2014)

Deep sequencing and analyses of miRNAs, isomiRs and miRNA induced silencing complex (miRISC)-associated miRNome in primary human chondrocytes
por: Haseeb, Abdul, et al.
Publicado: (2017)

Triphenylphosphonium conjugated gold nanotriangles impact Pi3K/AKT pathway in breast cancer cells: a photodynamic therapy approach
por: Vinita, Nadar Manimaran, et al.
Publicado: (2023)

A doxorubicin–platinum conjugate system: impacts on PI3K/AKT actuation and apoptosis in breast cancer cells
por: Patel, Puja, et al.
Publicado: (2021)

RISC without RISK?: an overview of current RISC computers in use in HEP batch
por: Jarp, S
Publicado: (1992)

Validity and reliability of the German versions of the CD-RISC-10 and CD-RISC-2
por: Wollny, Anna Irena, et al.
Publicado: (2021)

Microprocesadores RISC : evolución y tendencias /
Publicado: (2000)

Predicting Hospitalised Paediatric Pneumonia Mortality Risk: An External Validation of RISC and mRISC, and Local Tool Development (RISC-Malawi) from Malawi
por: Hooli, Shubhada, et al.
Publicado: (2016)

Correction: Predicting Hospitalised Paediatric Pneumonia Mortality Risk: An External Validation of RISC and mRISC, and Local Tool Development (RISC-Malawi) from Malawi
por: Hooli, Shubhada, et al.
Publicado: (2018)

AVR RISC microcontrollers handbook /
por: Kühnel, Claus, 1951-
Publicado: (1998)

RISC Technology and workstations report
Publicado: (1992)

Maelstrom functions in the production of Siwi-piRISC capable of regulating transposons in Bombyx germ cells
por: Namba, Yurika, et al.
Publicado: (2022)

Microprocessor architectures: RISC, CISC and DSP
por: Heath, Steve
Publicado: (1995)

Clarifying mammalian RISC assembly in vitro
por: Tan, Grace S, et al.
Publicado: (2011)

Diced Triplets Expose Neurons to RISC
por: Rudnicki, Dobrila D., et al.
Publicado: (2012)

Small Molecule Inhibition of RISC Loading
por: Tan, Grace S., et al.
Publicado: (2011)

Taking the RISC of exiting naïve pluripotency
por: Guallar, Diana, et al.
Publicado: (2016)

DEAD‐box polypeptide 43 facilitates piRNA amplification by actively liberating RNA from Ago3‐piRISC
por: Murakami, Ryo, et al.
Publicado: (2021)

Diffusion-weighted magnetic resonance imaging in acute reversible toxic leukoencephalopathy: A report of two cases
por: Sivasubramanian, S, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_qm5ei1flnnps2c5uqk66k2lgts