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Multi-Omics Analysis Revealed a Significant Alteration of Critical Metabolic Pathways Due to Sorafenib-Resistance in Hep3B Cell Lines

Hepatocellular carcinoma (HCC) is the second prominent cause of cancer-associated death worldwide. Usually, HCC is diagnosed in advanced stages, wherein sorafenib, a multiple target tyrosine kinase inhibitor, is used as the first line of treatment. Unfortunately, resistance to sorafenib is usually e...

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Detalles Bibliográficos
Autores principales: Abushawish, Kholoud Y. I., Soliman, Sameh S. M., Giddey, Alexander D., Al-Hroub, Hamza M., Mousa, Muath, Alzoubi, Karem H., El-Huneidi, Waseem, Abu-Gharbieh, Eman, Omar, Hany A., Elgendy, Sara M., Bustanji, Yasser, Soares, Nelson C., Semreen, Mohammad H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569810/
https://www.ncbi.nlm.nih.gov/pubmed/36233276
http://dx.doi.org/10.3390/ijms231911975

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