Nanoparticles Loaded with Platinum Drugs for Colorectal Cancer Therapy

Colorectal cancer is a common cancer in both men and women. Numerous studies on the therapeutic effectiveness of nanoparticles against colorectal cancer have been reported. Platinum treatments as well as other medications comprising of nanoparticles have been utilized. Drug resistance restricts the...

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Detalles Bibliográficos
Autores principales: Buyana, Buhle, Naki, Tobeka, Alven, Sibusiso, Aderibigbe, Blessing Atim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569963/
https://www.ncbi.nlm.nih.gov/pubmed/36232561
http://dx.doi.org/10.3390/ijms231911261
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author Buyana, Buhle
Naki, Tobeka
Alven, Sibusiso
Aderibigbe, Blessing Atim
author_facet Buyana, Buhle
Naki, Tobeka
Alven, Sibusiso
Aderibigbe, Blessing Atim
author_sort Buyana, Buhle
collection PubMed
description Colorectal cancer is a common cancer in both men and women. Numerous studies on the therapeutic effectiveness of nanoparticles against colorectal cancer have been reported. Platinum treatments as well as other medications comprising of nanoparticles have been utilized. Drug resistance restricts the use of platinum medicines, despite their considerable efficacy against a variety of cancers. This review reports clinically licensed platinum medicines (cisplatin, carboplatin, and oxaliplatin) combined with various nanoparticles that have been evaluated for their therapeutic efficacy in the treatment of colorectal cancer, including their mechanism of action, resistance, and limitations.
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spelling pubmed-95699632022-10-17 Nanoparticles Loaded with Platinum Drugs for Colorectal Cancer Therapy Buyana, Buhle Naki, Tobeka Alven, Sibusiso Aderibigbe, Blessing Atim Int J Mol Sci Review Colorectal cancer is a common cancer in both men and women. Numerous studies on the therapeutic effectiveness of nanoparticles against colorectal cancer have been reported. Platinum treatments as well as other medications comprising of nanoparticles have been utilized. Drug resistance restricts the use of platinum medicines, despite their considerable efficacy against a variety of cancers. This review reports clinically licensed platinum medicines (cisplatin, carboplatin, and oxaliplatin) combined with various nanoparticles that have been evaluated for their therapeutic efficacy in the treatment of colorectal cancer, including their mechanism of action, resistance, and limitations. MDPI 2022-09-24 /pmc/articles/PMC9569963/ /pubmed/36232561 http://dx.doi.org/10.3390/ijms231911261 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Buyana, Buhle
Naki, Tobeka
Alven, Sibusiso
Aderibigbe, Blessing Atim
Nanoparticles Loaded with Platinum Drugs for Colorectal Cancer Therapy
title Nanoparticles Loaded with Platinum Drugs for Colorectal Cancer Therapy
title_full Nanoparticles Loaded with Platinum Drugs for Colorectal Cancer Therapy
title_fullStr Nanoparticles Loaded with Platinum Drugs for Colorectal Cancer Therapy
title_full_unstemmed Nanoparticles Loaded with Platinum Drugs for Colorectal Cancer Therapy
title_short Nanoparticles Loaded with Platinum Drugs for Colorectal Cancer Therapy
title_sort nanoparticles loaded with platinum drugs for colorectal cancer therapy
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569963/
https://www.ncbi.nlm.nih.gov/pubmed/36232561
http://dx.doi.org/10.3390/ijms231911261
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