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Bio-Inorganic Layered Double Hydroxide Nanohybrids in Photochemotherapy: A Mini Review

Clay-based bio-inorganic nanohybrids, such as layered double hydroxides (LDH), have been extensively researched in the various fields of biomedicine, particularly for drug delivery and bio-imaging applications. Recent trends indicate that such two-dimensional LDH can be hybridized with a variety of...

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Detalles Bibliográficos
Autores principales: Rejinold, N. Sanoj, Choi, Goeun, Choy, Jin-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569973/
https://www.ncbi.nlm.nih.gov/pubmed/36233164
http://dx.doi.org/10.3390/ijms231911862
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author Rejinold, N. Sanoj
Choi, Goeun
Choy, Jin-Ho
author_facet Rejinold, N. Sanoj
Choi, Goeun
Choy, Jin-Ho
author_sort Rejinold, N. Sanoj
collection PubMed
description Clay-based bio-inorganic nanohybrids, such as layered double hydroxides (LDH), have been extensively researched in the various fields of biomedicine, particularly for drug delivery and bio-imaging applications. Recent trends indicate that such two-dimensional LDH can be hybridized with a variety of photo-active biomolecules to selectively achieve anti-cancer benefits through numerous photo/chemotherapies (PCT), including photothermal therapy, photodynamic therapy, and magnetic hyperthermia, a combination of therapies to achieve the best treatment regimen for patients that cannot be treated either by surgery or radiation alone. Among the novel two-dimensional clay-based bio-inorganic nanohybrids, LDH could enhance the photo-stability and drug release controllability of the PCT agents, which would, in turn, improve the overall phototherapeutic performance. This review article highlights the most recent advances in LDH-based two-dimensional clay-bio-inorganic nanohybrids for the aforementioned applications.
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spelling pubmed-95699732022-10-17 Bio-Inorganic Layered Double Hydroxide Nanohybrids in Photochemotherapy: A Mini Review Rejinold, N. Sanoj Choi, Goeun Choy, Jin-Ho Int J Mol Sci Review Clay-based bio-inorganic nanohybrids, such as layered double hydroxides (LDH), have been extensively researched in the various fields of biomedicine, particularly for drug delivery and bio-imaging applications. Recent trends indicate that such two-dimensional LDH can be hybridized with a variety of photo-active biomolecules to selectively achieve anti-cancer benefits through numerous photo/chemotherapies (PCT), including photothermal therapy, photodynamic therapy, and magnetic hyperthermia, a combination of therapies to achieve the best treatment regimen for patients that cannot be treated either by surgery or radiation alone. Among the novel two-dimensional clay-based bio-inorganic nanohybrids, LDH could enhance the photo-stability and drug release controllability of the PCT agents, which would, in turn, improve the overall phototherapeutic performance. This review article highlights the most recent advances in LDH-based two-dimensional clay-bio-inorganic nanohybrids for the aforementioned applications. MDPI 2022-10-06 /pmc/articles/PMC9569973/ /pubmed/36233164 http://dx.doi.org/10.3390/ijms231911862 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Rejinold, N. Sanoj
Choi, Goeun
Choy, Jin-Ho
Bio-Inorganic Layered Double Hydroxide Nanohybrids in Photochemotherapy: A Mini Review
title Bio-Inorganic Layered Double Hydroxide Nanohybrids in Photochemotherapy: A Mini Review
title_full Bio-Inorganic Layered Double Hydroxide Nanohybrids in Photochemotherapy: A Mini Review
title_fullStr Bio-Inorganic Layered Double Hydroxide Nanohybrids in Photochemotherapy: A Mini Review
title_full_unstemmed Bio-Inorganic Layered Double Hydroxide Nanohybrids in Photochemotherapy: A Mini Review
title_short Bio-Inorganic Layered Double Hydroxide Nanohybrids in Photochemotherapy: A Mini Review
title_sort bio-inorganic layered double hydroxide nanohybrids in photochemotherapy: a mini review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569973/
https://www.ncbi.nlm.nih.gov/pubmed/36233164
http://dx.doi.org/10.3390/ijms231911862
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