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Polo-Like Kinase 2 Plays an Essential Role in Cytoprotection against MG132-Induced Proteasome Inhibition via Phosphorylation of Serine 19 in HSPB5

Protein homeostasis, including protein folding, refolding, and degradation, is thought to decline with aging. HSPB5 (also known as αB-crystallin) prevents target protein aggregation as a molecular chaperone and exhibits a cytoprotective function against various cell stresses. To elucidate the effect...

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Detalles Bibliográficos
Autores principales:	Ueda, Shuji, Nishihara, Moeka, Hioka, Yuuki, Yoshino, Ken-ichi, Yamada, Soichiro, Yamanoue, Minoru, Shirai, Yasuhito
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9569985/ https://www.ncbi.nlm.nih.gov/pubmed/36232565 http://dx.doi.org/10.3390/ijms231911257

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