SHP-1/STAT3-Signaling-Axis-Regulated Coupling between BECN1 and SLC7A11 Contributes to Sorafenib-Induced Ferroptosis in Hepatocellular Carcinoma

Ferroptosis is a type of iron-dependent cell death pertaining to an excess of lipid peroxidation. It has been suggested that sorafenib—an anti-angiogenic medication for hepatocellular carcinoma (HCC)—induces ferroptosis, but the underlying mechanism for this remains largely unknown. We employed siRN...

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Detalles Bibliográficos
Autores principales: Huang, Chao-Yuan, Chen, Li-Ju, Chen, Grace, Chao, Tzu-I, Wang, Cheng-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570040/
https://www.ncbi.nlm.nih.gov/pubmed/36232407
http://dx.doi.org/10.3390/ijms231911092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570040/
https://www.ncbi.nlm.nih.gov/pubmed/36232407
http://dx.doi.org/10.3390/ijms231911092

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