Cargando…

Intratumoral Treatment with 5-Androstene-3β, 17α-Diol Reduces Tumor Size and Lung Metastasis in a Triple-Negative Experimental Model of Breast Cancer

Breast cancer treatment failure is related to low response rates, high costs, and long-term toxicities. Thus, it is necessary to find less toxic, cheaper, and more effective treatments. In situ administration ensures drug delivery to tumor cells and decreases systemic toxic effects. The androstene-3...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ruiz Manzano, Rocío Alejandra, Nava-Castro, Karen Elizabeth, Palacios-Arreola, Margarita Isabel, Hernández-Cervantes, Rosalía, Del Río-Araiza, Víctor Hugo, Segovia-Mendoza, Mariana, Pérez-Torres, Armando, Girón-Pérez, Manuel Iván, Morales-Montor, Jorge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570136/ https://www.ncbi.nlm.nih.gov/pubmed/36233245 http://dx.doi.org/10.3390/ijms231911944

Ejemplares similares

Potential Novel Risk Factor for Breast Cancer: Toxocara canis Infection Increases Tumor Size Due to Modulation of the Tumor Immune Microenvironment
por: Ruiz-Manzano, Rocío Alejandra, et al.
Publicado: (2020)

A single neonatal administration of Bisphenol A induces higher tumour weight associated to changes in tumour microenvironment in the adulthood
por: Palacios-Arreola, Margarita Isabel, et al.
Publicado: (2017)

The Endocrine Disruptor Compound Bisphenol-A (BPA) Regulates the Intra-Tumoral Immune Microenvironment and Increases Lung Metastasis in an Experimental Model of Breast Cancer
por: Palacios-Arreola, Margarita Isabel, et al.
Publicado: (2022)

Sex-associated protective effect of early bisphenol-A exposure during enteric infection with Trichinella spiralis in mice
por: Nava-Castro, Karen Elizabeth, et al.
Publicado: (2019)

Sex-Associated Differential mRNA Expression of Cytokines and Its Regulation by Sex Steroids in Different Brain Regions in a Plasmodium berghei ANKA Model of Cerebral Malaria
por: Legorreta-Herrera, Martha, et al.
Publicado: (2018)

Environmental Pollution to Blame for Depressive Disorder?
por: Segovia-Mendoza, Mariana, et al.
Publicado: (2022)

A novel progesterone receptor membrane component (PGRMC) in the human and swine parasite Taenia solium: implications to the host-parasite relationship
por: Aguilar-Díaz, Hugo, et al.
Publicado: (2018)

5-En-androstene-3 beta,17 beta-diol inhibits the growth of MCF-7 breast cancer cells when oestrogen receptors are blocked by oestradiol.
por: Boccuzzi, G., et al.
Publicado: (1994)

Microbial Modifications of Androstane and Androstene Steroids by Penicillium vinaceum
por: Panek, Anna, et al.
Publicado: (2020)

The neuro-steroid, 3β androstene 17α diol exhibits potent cytotoxic effects on human malignant glioma and lymphoma cells through different programmed cell death pathways
por: Graf, M R, et al.
Publicado: (2007)

AKR1C3 Converts Castrate and Post-Abiraterone DHEA-S into Testosterone to Stimulate Growth of Prostate Cancer Cells via 5-Androstene-3β,17β-Diol
por: Detlefsen, Andrea J., et al.
Publicado: (2023)

Gestational exposure to the cannabinoid WIN 55,212-2 and its effect on the innate intestinal immune response
por: Hernández-Cervantes, Rosalía, et al.
Publicado: (2019)

Neonatal Bisphenol A Exposure Affects the IgM Humoral Immune Response to 4T1 Breast Carcinoma Cells in Mice
por: Hernández Avila, Ricardo, et al.
Publicado: (2019)

Editorial: Exploring the breast tumor microenvironment: Association to metastasis, novel risk factors and novel treatments and immunotherapies
por: Nava-Castro, Karen Elizabeth, et al.
Publicado: (2022)

Environmental Pollution as a Risk Factor in Testicular Tumour Development: Focus on the Interaction between Bisphenol A and the Associated Immune Response
por: Nava-Castro, Karen Elizabeth, et al.
Publicado: (2019)

N-tert-Butyl-3-hydroxy-5-androstene-17-carboxamide monohydrate
por: Li, Jiang-Sheng, et al.
Publicado: (2009)

Structural Stereochemistry of Androstene Hormones Determines Interactions with Human Androgen, Estrogen, and Glucocorticoid Receptors
por: Shaak, Thomas L., et al.
Publicado: (2013)

Chronic exercise modulates the cellular immunity and its cannabinoid receptors expression
por: Valencia-Sánchez, Salvador, et al.
Publicado: (2019)

Neurosteroids as Selective Inhibitors of Glycine Receptor Activity: Structure-Activity Relationship Study on Endogenous Androstanes and Androstenes
por: Bukanova, Julia V., et al.
Publicado: (2020)

Immune Tumor Microenvironment in Breast Cancer and the Participation of Estrogen and Its Receptors in Cancer Physiopathology
por: Segovia-Mendoza, Mariana, et al.
Publicado: (2019)

A Novel 3-Phytosterone-9α-Hydroxylase Oxygenation Component and Its Application in Bioconversion of 4-Androstene-3,17-Dione to 9α-Hydroxy-4-Androstene-3,17-Dione Coupling with A NADH Regeneration Formate Dehydrogenase
por: Zhang, Xian, et al.
Publicado: (2019)

The deficiency of myelin in the mutant taiep rat induces a differential immune response related to protection from the human parasite Trichinella spiralis
por: Nava-Castro, Karen Elizabeth, et al.
Publicado: (2020)

Discovery of 16-Androstenes (Androstenone and Androstenol), Their Synthesis Pathway, and Possible Role in Reproduction of Mouse Deer (Moschiola indica)
por: Kumar, Vinod, et al.
Publicado: (2022)

Association of Serum Levels of Plasticizers Compounds, Phthalates and Bisphenols, in Patients and Survivors of Breast Cancer: A Real Connection?
por: Segovia-Mendoza, Mariana, et al.
Publicado: (2022)

The Role of Chemokines in Breast Cancer Pathology and Its Possible Use as Therapeutic Targets
por: Palacios-Arreola, M. Isabel, et al.
Publicado: (2014)

Tetrahydrofurandiols (THF-diols), Leukotoxindiols (LTX-diols), and Endocrine Disruption in Rats
por: Markaverich, Barry M., et al.
Publicado: (2007)

Tamoxifen Treatment in Hamsters Induces Protection during Taeniosis by Taenia solium
por: Escobedo, Galileo, et al.
Publicado: (2013)

Di-4-pyridylmethanediol
por: Knapp, Warren R., et al.
Publicado: (2008)

Efficient conversion of phytosterols into 4-androstene-3,17-dione and its C1,2-dehydrogenized and 9α-hydroxylated derivatives by engineered Mycobacteria
por: Li, Xin, et al.
Publicado: (2021)

Driving the conversion of phytosterol to 9α-hydroxy-4-androstene-3,17-dione in Mycolicibacterium neoaurum by engineering the supply and regeneration of flavin adenine dinucleotide
por: Song, Lu, et al.
Publicado: (2023)

Microbial production of short chain diols
por: Jiang, Yudong, et al.
Publicado: (2014)

Direct Copolymerization of CO(2) and Diols
por: Tamura, Masazumi, et al.
Publicado: (2016)

5-Androstene-3β,7β,17β-triol (β-AET) Slows Thermal Injury Induced Osteopenia in Mice: Relation to Aging and Osteoporosis
por: Malik, Ajay K., et al.
Publicado: (2010)

Sexual Dimorphism of the Neuroimmunoendocrine Response in the Spleen during a Helminth Infection: A New Role for an Old Player?
por: Nava-Castro, Karen Elizabeth, et al.
Publicado: (2022)

1-(3-Phenylisoxazol-5-yl)cyclohexane-1,2-diol
por: Astudillo, Luis, et al.
Publicado: (2009)

Intratumoral bidirectional transitions between epithelial and mesenchymal cells in triple‐negative breast cancer
por: Yamamoto, Mizuki, et al.
Publicado: (2017)

Molecular Targets for 17α-Ethynyl-5-Androstene-3β,7β,17β-Triol, an Anti-Inflammatory Agent Derived from the Human Metabolome
por: Reading, Christopher L., et al.
Publicado: (2012)

cis-Cycloheptane-1,2-diol
por: Betz, Richard, et al.
Publicado: (2009)

Chiral Diol-Based Organocatalysts in Enantioselective Reactions
por: Nguyen, Truong N., et al.
Publicado: (2018)

Synthesis of Siloxyalumoxanes and Alumosiloxanes Based on Organosilicon Diols
por: Shcherbakova, Galina, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_7r5bvfvdlvp5nvtgm721satict