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Hepatocyte-Specific Smad4 Deficiency Alleviates Liver Fibrosis via the p38/p65 Pathway

Liver fibrosis is a wound-healing response caused by the abnormal accumulation of extracellular matrix, which is produced by activated hepatic stellate cells (HSCs). Most studies have focused on the activated HSCs themselves in liver fibrosis, and whether hepatocytes can modulate the process of fibr...

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Detalles Bibliográficos
Autores principales: Wei, Miaomiao, Yan, Xinlong, Xin, Xin, Chen, Haiqiang, Hou, Lingling, Zhang, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570188/
https://www.ncbi.nlm.nih.gov/pubmed/36232998
http://dx.doi.org/10.3390/ijms231911696