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Targeting Phospholipase D Pharmacologically Prevents Phagocytic Function Loss of Retinal Pigment Epithelium Cells Exposed to High Glucose Levels

We previously described the participation of canonical phospholipase D isoforms (PLD1 and PLD2) in the inflammatory response of retinal pigment epithelium (RPE) cells exposed to high glucose concentrations (HG). Here, we studied the role of the PLD pathway in RPE phagocytic function. For this purpos...

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Detalles Bibliográficos
Autores principales: Bermúdez, Vicente, Tenconi, Paula Estefanía, Echevarría, María Sol, Asatrian, Aram, Calandria, Jorgelina Muriel, Giusto, Norma María, Bazan, Nicolas Guillermo, Mateos, Melina Valeria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570224/
https://www.ncbi.nlm.nih.gov/pubmed/36233124
http://dx.doi.org/10.3390/ijms231911823

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