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Keratocyte Differentiation Is Regulated by NF-κB and TGFβ Signaling Crosstalk

Interleukin-1 (IL-1) and transforming growth factor-beta (TGFβ) are important cytokines involved in corneal wound healing. Here, we studied the effect of these cytokines on corneal stromal cell (keratocyte) differentiation. IL-1β treatment resulted in reduced keratocyte phenotype, as evident by morp...

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Detalles Bibliográficos
Autores principales: Zhou, Xin, Li, Junhong, Backman, Ludvig J., Danielson, Patrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570283/
https://www.ncbi.nlm.nih.gov/pubmed/36232373
http://dx.doi.org/10.3390/ijms231911073