Knock-Out of the Five Lysyl-Oxidase Family Genes Enables Identification of Lysyl-Oxidase Pro-Enzyme Regulated Genes

The five lysyl-oxidase genes share similar enzymatic activities and contribute to tumor progression. We have knocked out the five lysyl-oxidase genes in MDA-MB-231 breast cancer cells using CRISPR/Cas9 in order to identify genes that are regulated by LOX but not by other lysyl-oxidases and in order...

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Detalles Bibliográficos
Autores principales: Liburkin-Dan, Tatyana, Nir-Zvi, Inbal, Razon, Hila, Kessler, Ofra, Neufeld, Gera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570307/
https://www.ncbi.nlm.nih.gov/pubmed/36232621
http://dx.doi.org/10.3390/ijms231911322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570307/
https://www.ncbi.nlm.nih.gov/pubmed/36232621
http://dx.doi.org/10.3390/ijms231911322

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