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Rational Design of a Thermostable 2′-Deoxyribosyltransferase for Nelarabine Production by Prediction of Disulfide Bond Engineering Sites

One of the major drawbacks of the industrial implementation of enzymatic processes is the low operational stability of the enzymes under tough industrial conditions. In this respect, the use of thermostable enzymes in the industry is gaining ground during the last decades. Herein, we report a struct...

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Detalles Bibliográficos
Autores principales: Cruz, Guillermo, Acosta, Javier, Mancheño, Jose Miguel, Del Arco, Jon, Fernández-Lucas, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570332/
https://www.ncbi.nlm.nih.gov/pubmed/36233108
http://dx.doi.org/10.3390/ijms231911806