A Convenient Way to Quinoxaline Derivatives through the Reaction of 2-(3-Oxoindolin-2-yl)-2-phenylacetonitriles with Benzene-1,2-diamines

Microwave-assisted reaction between 2-(3-oxoindolin-2-yl)-2-phenylacetonitriles andbenzene-1,2-diamines leads to the high-yielding formation of the corresponding quinoxalines as sole, easily isolaable products. The featured transformation involves unusual extrusion of phenylacetonitrile molecule and...

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Autores principales: Aksenov, Alexander V., Arutiunov, Nikolai A., Aksenov, Dmitrii A., Samovolov, Artem V., Kurenkov, Igor A., Aksenov, Nicolai A., Aleksandrova, Elena A., Momotova, Daria S., Rubin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
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Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570350/
https://www.ncbi.nlm.nih.gov/pubmed/36232422
http://dx.doi.org/10.3390/ijms231911120
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author Aksenov, Alexander V.
Arutiunov, Nikolai A.
Aksenov, Dmitrii A.
Samovolov, Artem V.
Kurenkov, Igor A.
Aksenov, Nicolai A.
Aleksandrova, Elena A.
Momotova, Daria S.
Rubin, Michael
author_facet Aksenov, Alexander V.
Arutiunov, Nikolai A.
Aksenov, Dmitrii A.
Samovolov, Artem V.
Kurenkov, Igor A.
Aksenov, Nicolai A.
Aleksandrova, Elena A.
Momotova, Daria S.
Rubin, Michael
author_sort Aksenov, Alexander V.
collection PubMed
description Microwave-assisted reaction between 2-(3-oxoindolin-2-yl)-2-phenylacetonitriles andbenzene-1,2-diamines leads to the high-yielding formation of the corresponding quinoxalines as sole, easily isolaable products. The featured transformation involves unusual extrusion of phenylacetonitrile molecule and could be performed in a short sequence starting from commonly available indoles and nitroolefins.
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spelling pubmed-95703502022-10-17 A Convenient Way to Quinoxaline Derivatives through the Reaction of 2-(3-Oxoindolin-2-yl)-2-phenylacetonitriles with Benzene-1,2-diamines Aksenov, Alexander V. Arutiunov, Nikolai A. Aksenov, Dmitrii A. Samovolov, Artem V. Kurenkov, Igor A. Aksenov, Nicolai A. Aleksandrova, Elena A. Momotova, Daria S. Rubin, Michael Int J Mol Sci Article Microwave-assisted reaction between 2-(3-oxoindolin-2-yl)-2-phenylacetonitriles andbenzene-1,2-diamines leads to the high-yielding formation of the corresponding quinoxalines as sole, easily isolaable products. The featured transformation involves unusual extrusion of phenylacetonitrile molecule and could be performed in a short sequence starting from commonly available indoles and nitroolefins. MDPI 2022-09-22 /pmc/articles/PMC9570350/ /pubmed/36232422 http://dx.doi.org/10.3390/ijms231911120 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Aksenov, Alexander V.
Arutiunov, Nikolai A.
Aksenov, Dmitrii A.
Samovolov, Artem V.
Kurenkov, Igor A.
Aksenov, Nicolai A.
Aleksandrova, Elena A.
Momotova, Daria S.
Rubin, Michael
A Convenient Way to Quinoxaline Derivatives through the Reaction of 2-(3-Oxoindolin-2-yl)-2-phenylacetonitriles with Benzene-1,2-diamines
title A Convenient Way to Quinoxaline Derivatives through the Reaction of 2-(3-Oxoindolin-2-yl)-2-phenylacetonitriles with Benzene-1,2-diamines
title_full A Convenient Way to Quinoxaline Derivatives through the Reaction of 2-(3-Oxoindolin-2-yl)-2-phenylacetonitriles with Benzene-1,2-diamines
title_fullStr A Convenient Way to Quinoxaline Derivatives through the Reaction of 2-(3-Oxoindolin-2-yl)-2-phenylacetonitriles with Benzene-1,2-diamines
title_full_unstemmed A Convenient Way to Quinoxaline Derivatives through the Reaction of 2-(3-Oxoindolin-2-yl)-2-phenylacetonitriles with Benzene-1,2-diamines
title_short A Convenient Way to Quinoxaline Derivatives through the Reaction of 2-(3-Oxoindolin-2-yl)-2-phenylacetonitriles with Benzene-1,2-diamines
title_sort convenient way to quinoxaline derivatives through the reaction of 2-(3-oxoindolin-2-yl)-2-phenylacetonitriles with benzene-1,2-diamines
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570350/
https://www.ncbi.nlm.nih.gov/pubmed/36232422
http://dx.doi.org/10.3390/ijms231911120
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