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Somatic Mutational Landscape in Mexican Patients: CDH1 Mutations and chr20q13.33 Amplifications Are Associated with Diffuse-Type Gastric Adenocarcinoma
The Hispanic population, compared with other ethnic groups, presents a more aggressive gastric cancer phenotype with higher frequency of diffuse-type gastric adenocarcinoma (GA); this could be related to the mutational landscape of GA in these patients. Using whole-exome sequencing, we sought to pre...
Autores principales: | Cerrato-Izaguirre, Dennis, Chirino, Yolanda I., Prada, Diddier, Quezada-Maldonado, Ericka Marel, Herrera, Luis A, Hernández-Guerrero, Angélica, Alonso-Larraga, Juan Octavio, Herrera-Goepfert, Roberto, Oñate-Ocaña, Luis F., Cantú-de-León, David, Meneses-García, Abelardo, Basurto-Lozada, Patricia, Robles-Espinoza, Carla Daniela, Camacho, Javier, García-Cuellar, Claudia M., Sánchez-Pérez, Yesennia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570354/ https://www.ncbi.nlm.nih.gov/pubmed/36232418 http://dx.doi.org/10.3390/ijms231911116 |
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