Conformational Preferences of Pyridone Adenine Dinucleotides from Molecular Dynamics Simulations

Pyridone adenine dinucleotides (ox-NADs) are redox inactive derivatives of the enzyme cofactor and substrate nicotinamide adenine dinucleotide (NAD) that have a carbonyl group at the C2, C4, or C6 positions of the nicotinamide ring. These aberrant cofactor analogs accumulate in cells under stress an...

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Detalles Bibliográficos
Autores principales: Buckley, David P., Migaud, Marie E., Tanner, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570408/
https://www.ncbi.nlm.nih.gov/pubmed/36233167
http://dx.doi.org/10.3390/ijms231911866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570408/
https://www.ncbi.nlm.nih.gov/pubmed/36233167
http://dx.doi.org/10.3390/ijms231911866

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