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Conformational Preferences of Pyridone Adenine Dinucleotides from Molecular Dynamics Simulations
Pyridone adenine dinucleotides (ox-NADs) are redox inactive derivatives of the enzyme cofactor and substrate nicotinamide adenine dinucleotide (NAD) that have a carbonyl group at the C2, C4, or C6 positions of the nicotinamide ring. These aberrant cofactor analogs accumulate in cells under stress an...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570408/ https://www.ncbi.nlm.nih.gov/pubmed/36233167 http://dx.doi.org/10.3390/ijms231911866 |