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Polyphyllin II Induces Protective Autophagy and Apoptosis via Inhibiting PI3K/AKT/mTOR and STAT3 Signaling in Colorectal Cancer Cells
Polyphyllin II (PPII) is a natural steroidal saponin occurring in Rhizoma Paridis. It has been demonstrated to exhibit anti-cancer activity against a variety of cancer cells. However, the anti-colorectal cancer (CRC) effects and mechanism of action of PPII are rarely reported. In the present study,...
Autores principales: | Li, Jun-Kui, Sun, Hai-Tao, Jiang, Xiao-Li, Chen, Yi-Fei, Zhang, Zhu, Wang, Ying, Chen, Wen-Qing, Zhang, Zhang, Sze, Stephen Cho Wing, Zhu, Pei-Li, Yung, Ken Kin Lam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570434/ https://www.ncbi.nlm.nih.gov/pubmed/36233191 http://dx.doi.org/10.3390/ijms231911890 |
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