Cargando…

Nucleotide-Induced Nanoscale Changes in the Mechanical Properties of Rat Cerebellar Astrocytes: Selective Stimulation and Blocking of the Purinergic Receptor P2X7 †

As members of the family of nucleotide receptors, P2X7 receptors are of particular interest due to their unique structural and pharmacological characteristics. As ATP-gated ionic channels, P2X7 receptors in their activation elicit membrane depolarization; extracellular calcium influx; and activation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Gil-Redondo, Juan Carlos, Iturri, Jagoba, Trueba, Yaiza, Benito-León, María, Pérez-Sen, Raquel, Delicado, Esmerilda G., Toca-Herrera, José Luis, Ortega, Felipe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570466/ https://www.ncbi.nlm.nih.gov/pubmed/36233228 http://dx.doi.org/10.3390/ijms231911927

Ejemplares similares

Nucleotides-Induced Changes in the Mechanical Properties of Living Endothelial Cells and Astrocytes, Analyzed by Atomic Force Microscopy
por: Gil-Redondo, Juan Carlos, et al.
Publicado: (2021)

Dissecting the Purinergic Signaling Puzzle
por: Pérez-Sen, Raquel, et al.
Publicado: (2021)

P2X7 Nucleotide and EGF Receptors Exert Dual Modulation of the Dual-Specificity Phosphatase 6 (MKP-3) in Granule Neurons and Astrocytes, Contributing to Negative Feedback on ERK Signaling
por: Queipo, Mª José, et al.
Publicado: (2018)

P2X7, NMDA and BDNF receptors converge on GSK3 phosphorylation and cooperate to promote survival in cerebellar granule neurons
por: Ortega, Felipe, et al.
Publicado: (2010)

Characterization of Cell Scaffolds by Atomic Force Microscopy
por: Iturri, Jagoba, et al.
Publicado: (2017)

Cerebellar astrocytes co-express several ADP receptors. Presence of functional P2Y(13)-like receptors
por: Carrasquero, Luz María G., et al.
Publicado: (2005)

BCI, an inhibitor of the DUSP1 and DUSP6 dual specificity phosphatases, enhances P2X7 receptor expression in neuroblastoma cells
por: Benito-León, María, et al.
Publicado: (2022)

Prostaglandin E(2) Impairs P2Y(2)/P2Y(4) Receptor Signaling in Cerebellar Astrocytes via EP3 Receptors
por: Paniagua-Herranz, Lucía, et al.
Publicado: (2017)

Neuroprotection Mediated by P2Y(13) Nucleotide Receptors in Neurons
por: Pérez-Sen, Raquel, et al.
Publicado: (2015)

Physiopathological Role of the Vesicular Nucleotide Transporter (VNUT) in the Central Nervous System: Relevance of the Vesicular Nucleotide Release as a Potential Therapeutic Target
por: Miras-Portugal, María T., et al.
Publicado: (2019)

In‐situ 2D bacterial crystal growth as a function of protein concentration: An atomic force microscopy study
por: Moreno‐Cencerrado, Alberto, et al.
Publicado: (2018)

Measuring biomaterials mechanics with atomic force microscopy. 1. Influence of the loading rate and applied force (pyramidal tips)
por: Weber, Andreas, et al.
Publicado: (2019)

Single-Cell Probe Force Studies to Identify Sox2 Overexpression-Promoted Cell Adhesion in MCF7 Breast Cancer Cells
por: Iturri, Jagoba, et al.
Publicado: (2020)

Combining low-density cell culture, single-cell tracking, and patch-clamp to monitor the behavior of postnatal murine cerebellar neural stem cells
por: Menéndez-Méndez, Aida, et al.
Publicado: (2021)

Dual-Specificity Phosphatase Regulation in Neurons and Glial Cells
por: Pérez-Sen, Raquel, et al.
Publicado: (2019)

In Vitro Characterization of the Two-Stage Non-Classical Reassembly Pathway of S-Layers
por: Breitwieser, Andreas, et al.
Publicado: (2017)

Microtubule disruption changes endothelial cell mechanics and adhesion
por: Weber, Andreas, et al.
Publicado: (2019)

Estrogen Modulates Epithelial Breast Cancer Cell Mechanics and Cell-to-Cell Contacts
por: Zbiral, Barbara, et al.
Publicado: (2021)

Live Imaging Reveals Cerebellar Neural Stem Cell Dynamics and the Role of VNUT in Lineage Progression
por: Paniagua-Herranz, Lucía, et al.
Publicado: (2020)

Influencing the adhesion properties and wettability of mucin protein films by variation of the environmental pH
por: Sumarokova, Maria, et al.
Publicado: (2018)

Correction: Novel biodegradable and non-fouling systems for controlled-release based on poly(ε-caprolactone)/Quercetin blends and biomimetic bacterial S-layer coatings
por: Sanchez-Rexach, Eva, et al.
Publicado: (2019)

Novel biodegradable and non-fouling systems for controlled-release based on poly(ε-caprolactone)/Quercetin blends and biomimetic bacterial S-layer coatings
por: Sanchez-Rexach, Eva, et al.
Publicado: (2019)

Impact of surface wettability on S-layer recrystallization: a real-time characterization by QCM-D
por: Iturri, Jagoba, et al.
Publicado: (2017)

Resveratrol-Induced Temporal Variation in the Mechanical Properties of MCF-7 Breast Cancer Cells Investigated by Atomic Force Microscopy
por: Iturri, Jagoba, et al.
Publicado: (2019)

Time- and Zinc-Related Changes in Biomechanical Properties of Human Colorectal Cancer Cells Examined by Atomic Force Microscopy
por: Maares, Maria, et al.
Publicado: (2020)

Microglia trigger astrocyte-mediated neuroprotection via purinergic gliotransmission
por: Shinozaki, Youichi, et al.
Publicado: (2014)

An autocrine purinergic signaling controls astrocyte-induced neuronal excitation
por: Shen, Weida, et al.
Publicado: (2017)

Therapeutic Potential of Astrocyte Purinergic Signalling in Epilepsy and Multiple Sclerosis
por: Nobili, Paola, et al.
Publicado: (2022)

Dopaminergic Neurotoxicants Cause Biphasic Inhibition of Purinergic Calcium Signaling in Astrocytes
por: Streifel, Karin M., et al.
Publicado: (2014)

Purinergic responses of calcium-dependent signaling pathways in cultured adult human astrocytes
por: Hashioka, Sadayuki, et al.
Publicado: (2014)

Purinergic Signaling in Neuron-Astrocyte Interactions, Circadian Rhythms, and Alcohol Use Disorder
por: Lindberg, Daniel, et al.
Publicado: (2018)

Sustained Release of Prostaglandin E(2) in Fibroblasts Expressing Ectopically Cyclooxygenase 2 Impairs P2Y-Dependent Ca(2+)-Mobilization
por: Pimentel-Santillana, María, et al.
Publicado: (2014)

Measuring biological materials mechanics with atomic force microscopy ‐ Mechanical unfolding of biopolymers
por: Gil‐Redondo, Juan Carlos, et al.
Publicado: (2022)

Live Imaging Followed by Single Cell Tracking to Monitor Cell Biology and the Lineage Progression of Multiple Neural Populations
por: Gómez-Villafuertes, Rosa, et al.
Publicado: (2017)

Metabolic Heterogeneity of Cerebral Cortical and Cerebellar Astrocytes
por: Sun, Yuanhong, et al.
Publicado: (2023)

Nanoscale Phosphoinositide Distribution on Cell Membranes of Mouse Cerebellar Neurons
por: Eguchi, Kohgaku, et al.
Publicado: (2023)

The Role of Nucleotides and Purinergic Signaling in Apoptotic Cell Clearance – Implications for Chronic Inflammatory Diseases
por: Chen, Jin, et al.
Publicado: (2014)

A role for the purinergic receptor P2X(3) in astrocytes in the mechanism of craniofacial neuropathic pain
por: Mah, Won, et al.
Publicado: (2017)

Specific Temporal Distribution and Subcellular Localization of a Functional Vesicular Nucleotide Transporter (VNUT) in Cerebellar Granule Neurons
por: Menéndez-Méndez, Aida, et al.
Publicado: (2017)

Guanosine-Based Nucleotides, the Sons of a Lesser God in the Purinergic Signal Scenario of Excitable Tissues
por: Mancinelli, Rosa, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_gfqc98osfkbs6ulevgt1v6lmhu