Cargando…
Novel Morpholine-Bearing Quinoline Derivatives as Potential Cholinesterase Inhibitors: The Influence of Amine, Carbon Linkers and Phenylamino Groups
A series of novel 4-N-phenylaminoquinoline derivatives containing a morpholine group were designed and synthesized, and their anti-cholinesterase activities and ABTS radical-scavenging activities were tested. Among them, compounds 11a, 11g, 11h, 11j, 11l, and 12a had comparable inhibition activities...
Autores principales: | Liu, Cheng, Wang, Li-Ning, Liu, Yu-Ming |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570490/ https://www.ncbi.nlm.nih.gov/pubmed/36232533 http://dx.doi.org/10.3390/ijms231911231 |
Ejemplares similares
-
Phenoxyethyl Piperidine/Morpholine Derivatives as PAS and CAS Inhibitors of Cholinesterases: Insights for Future Drug Design
por: Pourshojaei, Yaghoub, et al.
Publicado: (2019) -
Synthesis, Characterization, and Crystal Structures of Imides Condensed with p-Phenylamino(Phenyl) Amine and Fluorescence Property
por: Zhang, Jing, et al.
Publicado: (2019) -
Quinolin-3-amine
por: Islor, Arun M., et al.
Publicado: (2012) -
Development of (4-Phenylamino)quinazoline Alkylthiourea Derivatives as Novel NF-κB Inhibitors
por: Darwish, Sarah S., et al.
Publicado: (2022) -
Computational Screening of Phenylamino-Phenoxy-Quinoline Derivatives against the Main Protease of SARS-CoV-2 Using Molecular Docking and the ONIOM Method
por: Patnin, Suwicha, et al.
Publicado: (2022)