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Initial Vestibular Function May Be Associated with Future Postural Instability in Parkinson’s Disease
Backgrounds: We aimed to understand the association between initial vestibular function examination and postural instability (PI) development in Parkinson’s disease (PD). Methods: After screening 51 PD patients, we divided 31 patients into 2 groups based on the presence of PI at the follow-up visit...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570519/ https://www.ncbi.nlm.nih.gov/pubmed/36233475 http://dx.doi.org/10.3390/jcm11195608 |
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author | Park, Jeong Ho Kim, Min Seung Kang, Suk Yun |
author_facet | Park, Jeong Ho Kim, Min Seung Kang, Suk Yun |
author_sort | Park, Jeong Ho |
collection | PubMed |
description | Backgrounds: We aimed to understand the association between initial vestibular function examination and postural instability (PI) development in Parkinson’s disease (PD). Methods: After screening 51 PD patients, we divided 31 patients into 2 groups based on the presence of PI at the follow-up visit and compared the clinical features and vestibular-evoked myogenic potential (VEMP) variables. Results: The mean values of Hoehn and Yahr stage, Unified Parkinson’s Disease Rating Scale (UPDRS) part III, and item 30 (postural stability) of UPDRS were larger in patients with PI at a follow-up visit (p = 0.000, 0.006, 0.048, respectively). In VEMP analyses, the onset latencies of left and right cervical VEMPs were significantly reduced in patients with PI (p = 0.013, 0.040, respectively). Conclusion: We found that the initial VEMP test may be associated with later postural imbalance in PD, suggesting the baseline evaluation may help predict future PI occurrence. A more significant number of patients and more long-term follow-ups are likely to be required for confirmation. |
format | Online Article Text |
id | pubmed-9570519 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-95705192022-10-17 Initial Vestibular Function May Be Associated with Future Postural Instability in Parkinson’s Disease Park, Jeong Ho Kim, Min Seung Kang, Suk Yun J Clin Med Article Backgrounds: We aimed to understand the association between initial vestibular function examination and postural instability (PI) development in Parkinson’s disease (PD). Methods: After screening 51 PD patients, we divided 31 patients into 2 groups based on the presence of PI at the follow-up visit and compared the clinical features and vestibular-evoked myogenic potential (VEMP) variables. Results: The mean values of Hoehn and Yahr stage, Unified Parkinson’s Disease Rating Scale (UPDRS) part III, and item 30 (postural stability) of UPDRS were larger in patients with PI at a follow-up visit (p = 0.000, 0.006, 0.048, respectively). In VEMP analyses, the onset latencies of left and right cervical VEMPs were significantly reduced in patients with PI (p = 0.013, 0.040, respectively). Conclusion: We found that the initial VEMP test may be associated with later postural imbalance in PD, suggesting the baseline evaluation may help predict future PI occurrence. A more significant number of patients and more long-term follow-ups are likely to be required for confirmation. MDPI 2022-09-23 /pmc/articles/PMC9570519/ /pubmed/36233475 http://dx.doi.org/10.3390/jcm11195608 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Park, Jeong Ho Kim, Min Seung Kang, Suk Yun Initial Vestibular Function May Be Associated with Future Postural Instability in Parkinson’s Disease |
title | Initial Vestibular Function May Be Associated with Future Postural Instability in Parkinson’s Disease |
title_full | Initial Vestibular Function May Be Associated with Future Postural Instability in Parkinson’s Disease |
title_fullStr | Initial Vestibular Function May Be Associated with Future Postural Instability in Parkinson’s Disease |
title_full_unstemmed | Initial Vestibular Function May Be Associated with Future Postural Instability in Parkinson’s Disease |
title_short | Initial Vestibular Function May Be Associated with Future Postural Instability in Parkinson’s Disease |
title_sort | initial vestibular function may be associated with future postural instability in parkinson’s disease |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570519/ https://www.ncbi.nlm.nih.gov/pubmed/36233475 http://dx.doi.org/10.3390/jcm11195608 |
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