High Endogenously Synthesized N-3 Polyunsaturated Fatty Acids in Fat-1 Mice Attenuate High-Fat Diet-Induced Insulin Resistance by Inhibiting NLRP3 Inflammasome Activation via Akt/GSK-3β/TXNIP Pathway

High-fat (HF) diets and low-grade chronic inflammation contribute to the development of insulin resistance and type 2 diabetes (T2D), whereas n-3 polyunsaturated fatty acids (PUFAs), due to their anti-inflammatory effects, protect against insulin resistance. Interleukin (IL)-1β is implicated in insu...

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Detalles Bibliográficos
Autores principales: Zhu, Pan, Zhang, Jin-Jie, Cen, Yi, Yang, Yong, Wang, Feng, Gu, Kun-Peng, Yang, Hai-Tao, Wang, Yun-Zhi, Zou, Zu-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570616/
https://www.ncbi.nlm.nih.gov/pubmed/36234919
http://dx.doi.org/10.3390/molecules27196384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570616/
https://www.ncbi.nlm.nih.gov/pubmed/36234919
http://dx.doi.org/10.3390/molecules27196384

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