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Chitosan Nanoparticles: A Versatile Platform for Biomedical Applications

Chitosan is a biodegradable and biocompatible natural polymer that has been extensively explored in recent decades. The Food and Drug Administration has approved chitosan for wound treatment and nutritional use. Furthermore, chitosan has paved the way for advancements in different biomedical applica...

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Autores principales: Bashir, Showkeen Muzamil, Ahmed Rather, Gulzar, Patrício, Ana, Haq, Zulfiqar, Sheikh, Amir Amin, Shah, Mohd Zahoor ul Haq, Singh, Hemant, Khan, Azmat Alam, Imtiyaz, Sofi, Ahmad, Sheikh Bilal, Nabi, Showket, Rakhshan, Rabia, Hassan, Saqib, Fonte, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570720/
https://www.ncbi.nlm.nih.gov/pubmed/36233864
http://dx.doi.org/10.3390/ma15196521
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author Bashir, Showkeen Muzamil
Ahmed Rather, Gulzar
Patrício, Ana
Haq, Zulfiqar
Sheikh, Amir Amin
Shah, Mohd Zahoor ul Haq
Singh, Hemant
Khan, Azmat Alam
Imtiyaz, Sofi
Ahmad, Sheikh Bilal
Nabi, Showket
Rakhshan, Rabia
Hassan, Saqib
Fonte, Pedro
author_facet Bashir, Showkeen Muzamil
Ahmed Rather, Gulzar
Patrício, Ana
Haq, Zulfiqar
Sheikh, Amir Amin
Shah, Mohd Zahoor ul Haq
Singh, Hemant
Khan, Azmat Alam
Imtiyaz, Sofi
Ahmad, Sheikh Bilal
Nabi, Showket
Rakhshan, Rabia
Hassan, Saqib
Fonte, Pedro
author_sort Bashir, Showkeen Muzamil
collection PubMed
description Chitosan is a biodegradable and biocompatible natural polymer that has been extensively explored in recent decades. The Food and Drug Administration has approved chitosan for wound treatment and nutritional use. Furthermore, chitosan has paved the way for advancements in different biomedical applications including as a nanocarrier and tissue-engineering scaffold. Its antibacterial, antioxidant, and haemostatic properties make it an excellent option for wound dressings. Because of its hydrophilic nature, chitosan is an ideal starting material for biocompatible and biodegradable hydrogels. To suit specific application demands, chitosan can be combined with fillers, such as hydroxyapatite, to modify the mechanical characteristics of pH-sensitive hydrogels. Furthermore, the cationic characteristics of chitosan have made it a popular choice for gene delivery and cancer therapy. Thus, the use of chitosan nanoparticles in developing novel drug delivery systems has received special attention. This review aims to provide an overview of chitosan-based nanoparticles, focusing on their versatile properties and different applications in biomedical sciences and engineering.
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spelling pubmed-95707202022-10-17 Chitosan Nanoparticles: A Versatile Platform for Biomedical Applications Bashir, Showkeen Muzamil Ahmed Rather, Gulzar Patrício, Ana Haq, Zulfiqar Sheikh, Amir Amin Shah, Mohd Zahoor ul Haq Singh, Hemant Khan, Azmat Alam Imtiyaz, Sofi Ahmad, Sheikh Bilal Nabi, Showket Rakhshan, Rabia Hassan, Saqib Fonte, Pedro Materials (Basel) Review Chitosan is a biodegradable and biocompatible natural polymer that has been extensively explored in recent decades. The Food and Drug Administration has approved chitosan for wound treatment and nutritional use. Furthermore, chitosan has paved the way for advancements in different biomedical applications including as a nanocarrier and tissue-engineering scaffold. Its antibacterial, antioxidant, and haemostatic properties make it an excellent option for wound dressings. Because of its hydrophilic nature, chitosan is an ideal starting material for biocompatible and biodegradable hydrogels. To suit specific application demands, chitosan can be combined with fillers, such as hydroxyapatite, to modify the mechanical characteristics of pH-sensitive hydrogels. Furthermore, the cationic characteristics of chitosan have made it a popular choice for gene delivery and cancer therapy. Thus, the use of chitosan nanoparticles in developing novel drug delivery systems has received special attention. This review aims to provide an overview of chitosan-based nanoparticles, focusing on their versatile properties and different applications in biomedical sciences and engineering. MDPI 2022-09-20 /pmc/articles/PMC9570720/ /pubmed/36233864 http://dx.doi.org/10.3390/ma15196521 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Bashir, Showkeen Muzamil
Ahmed Rather, Gulzar
Patrício, Ana
Haq, Zulfiqar
Sheikh, Amir Amin
Shah, Mohd Zahoor ul Haq
Singh, Hemant
Khan, Azmat Alam
Imtiyaz, Sofi
Ahmad, Sheikh Bilal
Nabi, Showket
Rakhshan, Rabia
Hassan, Saqib
Fonte, Pedro
Chitosan Nanoparticles: A Versatile Platform for Biomedical Applications
title Chitosan Nanoparticles: A Versatile Platform for Biomedical Applications
title_full Chitosan Nanoparticles: A Versatile Platform for Biomedical Applications
title_fullStr Chitosan Nanoparticles: A Versatile Platform for Biomedical Applications
title_full_unstemmed Chitosan Nanoparticles: A Versatile Platform for Biomedical Applications
title_short Chitosan Nanoparticles: A Versatile Platform for Biomedical Applications
title_sort chitosan nanoparticles: a versatile platform for biomedical applications
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570720/
https://www.ncbi.nlm.nih.gov/pubmed/36233864
http://dx.doi.org/10.3390/ma15196521
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