Cargando…

Automated Detection of Sleep Apnea-Hypopnea Events Based on 60 GHz Frequency-Modulated Continuous-Wave Radar Using Convolutional Recurrent Neural Networks: A Preliminary Report of a Prospective Cohort Study

Radar is a promising non-contact sensor for overnight polysomnography (PSG), the gold standard for diagnosing obstructive sleep apnea (OSA). This preliminary study aimed to demonstrate the feasibility of the automated detection of apnea-hypopnea events for OSA diagnosis based on 60 GHz frequency-mod...

Descripción completa

Detalles Bibliográficos
Autores principales: Choi, Jae Won, Kim, Dong Hyun, Koo, Dae Lim, Park, Yangmi, Nam, Hyunwoo, Lee, Ji Hyun, Kim, Hyo Jin, Hong, Seung-No, Jang, Gwangsoo, Lim, Sungmook, Kim, Baekhyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570824/
https://www.ncbi.nlm.nih.gov/pubmed/36236274
http://dx.doi.org/10.3390/s22197177
_version_ 1784810206868275200
author Choi, Jae Won
Kim, Dong Hyun
Koo, Dae Lim
Park, Yangmi
Nam, Hyunwoo
Lee, Ji Hyun
Kim, Hyo Jin
Hong, Seung-No
Jang, Gwangsoo
Lim, Sungmook
Kim, Baekhyun
author_facet Choi, Jae Won
Kim, Dong Hyun
Koo, Dae Lim
Park, Yangmi
Nam, Hyunwoo
Lee, Ji Hyun
Kim, Hyo Jin
Hong, Seung-No
Jang, Gwangsoo
Lim, Sungmook
Kim, Baekhyun
author_sort Choi, Jae Won
collection PubMed
description Radar is a promising non-contact sensor for overnight polysomnography (PSG), the gold standard for diagnosing obstructive sleep apnea (OSA). This preliminary study aimed to demonstrate the feasibility of the automated detection of apnea-hypopnea events for OSA diagnosis based on 60 GHz frequency-modulated continuous-wave radar using convolutional recurrent neural networks. The dataset comprised 44 participants from an ongoing OSA cohort, recruited from July 2021 to April 2022, who underwent overnight PSG with a radar sensor. All PSG recordings, including sleep and wakefulness, were included in the dataset. Model development and evaluation were based on a five-fold cross-validation. The area under the receiver operating characteristic curve for the classification of 1-min segments ranged from 0.796 to 0.859. Depending on OSA severity, the sensitivities for apnea-hypopnea events were 49.0–67.6%, and the number of false-positive detections per participant was 23.4–52.8. The estimated apnea-hypopnea index showed strong correlations (Pearson correlation coefficient = 0.805–0.949) and good to excellent agreement (intraclass correlation coefficient = 0.776–0.929) with the ground truth. There was substantial agreement between the estimated and ground truth OSA severity (kappa statistics = 0.648–0.736). The results demonstrate the potential of radar as a standalone screening tool for OSA.
format Online
Article
Text
id pubmed-9570824
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-95708242022-10-17 Automated Detection of Sleep Apnea-Hypopnea Events Based on 60 GHz Frequency-Modulated Continuous-Wave Radar Using Convolutional Recurrent Neural Networks: A Preliminary Report of a Prospective Cohort Study Choi, Jae Won Kim, Dong Hyun Koo, Dae Lim Park, Yangmi Nam, Hyunwoo Lee, Ji Hyun Kim, Hyo Jin Hong, Seung-No Jang, Gwangsoo Lim, Sungmook Kim, Baekhyun Sensors (Basel) Article Radar is a promising non-contact sensor for overnight polysomnography (PSG), the gold standard for diagnosing obstructive sleep apnea (OSA). This preliminary study aimed to demonstrate the feasibility of the automated detection of apnea-hypopnea events for OSA diagnosis based on 60 GHz frequency-modulated continuous-wave radar using convolutional recurrent neural networks. The dataset comprised 44 participants from an ongoing OSA cohort, recruited from July 2021 to April 2022, who underwent overnight PSG with a radar sensor. All PSG recordings, including sleep and wakefulness, were included in the dataset. Model development and evaluation were based on a five-fold cross-validation. The area under the receiver operating characteristic curve for the classification of 1-min segments ranged from 0.796 to 0.859. Depending on OSA severity, the sensitivities for apnea-hypopnea events were 49.0–67.6%, and the number of false-positive detections per participant was 23.4–52.8. The estimated apnea-hypopnea index showed strong correlations (Pearson correlation coefficient = 0.805–0.949) and good to excellent agreement (intraclass correlation coefficient = 0.776–0.929) with the ground truth. There was substantial agreement between the estimated and ground truth OSA severity (kappa statistics = 0.648–0.736). The results demonstrate the potential of radar as a standalone screening tool for OSA. MDPI 2022-09-21 /pmc/articles/PMC9570824/ /pubmed/36236274 http://dx.doi.org/10.3390/s22197177 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Choi, Jae Won
Kim, Dong Hyun
Koo, Dae Lim
Park, Yangmi
Nam, Hyunwoo
Lee, Ji Hyun
Kim, Hyo Jin
Hong, Seung-No
Jang, Gwangsoo
Lim, Sungmook
Kim, Baekhyun
Automated Detection of Sleep Apnea-Hypopnea Events Based on 60 GHz Frequency-Modulated Continuous-Wave Radar Using Convolutional Recurrent Neural Networks: A Preliminary Report of a Prospective Cohort Study
title Automated Detection of Sleep Apnea-Hypopnea Events Based on 60 GHz Frequency-Modulated Continuous-Wave Radar Using Convolutional Recurrent Neural Networks: A Preliminary Report of a Prospective Cohort Study
title_full Automated Detection of Sleep Apnea-Hypopnea Events Based on 60 GHz Frequency-Modulated Continuous-Wave Radar Using Convolutional Recurrent Neural Networks: A Preliminary Report of a Prospective Cohort Study
title_fullStr Automated Detection of Sleep Apnea-Hypopnea Events Based on 60 GHz Frequency-Modulated Continuous-Wave Radar Using Convolutional Recurrent Neural Networks: A Preliminary Report of a Prospective Cohort Study
title_full_unstemmed Automated Detection of Sleep Apnea-Hypopnea Events Based on 60 GHz Frequency-Modulated Continuous-Wave Radar Using Convolutional Recurrent Neural Networks: A Preliminary Report of a Prospective Cohort Study
title_short Automated Detection of Sleep Apnea-Hypopnea Events Based on 60 GHz Frequency-Modulated Continuous-Wave Radar Using Convolutional Recurrent Neural Networks: A Preliminary Report of a Prospective Cohort Study
title_sort automated detection of sleep apnea-hypopnea events based on 60 ghz frequency-modulated continuous-wave radar using convolutional recurrent neural networks: a preliminary report of a prospective cohort study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570824/
https://www.ncbi.nlm.nih.gov/pubmed/36236274
http://dx.doi.org/10.3390/s22197177
work_keys_str_mv AT choijaewon automateddetectionofsleepapneahypopneaeventsbasedon60ghzfrequencymodulatedcontinuouswaveradarusingconvolutionalrecurrentneuralnetworksapreliminaryreportofaprospectivecohortstudy
AT kimdonghyun automateddetectionofsleepapneahypopneaeventsbasedon60ghzfrequencymodulatedcontinuouswaveradarusingconvolutionalrecurrentneuralnetworksapreliminaryreportofaprospectivecohortstudy
AT koodaelim automateddetectionofsleepapneahypopneaeventsbasedon60ghzfrequencymodulatedcontinuouswaveradarusingconvolutionalrecurrentneuralnetworksapreliminaryreportofaprospectivecohortstudy
AT parkyangmi automateddetectionofsleepapneahypopneaeventsbasedon60ghzfrequencymodulatedcontinuouswaveradarusingconvolutionalrecurrentneuralnetworksapreliminaryreportofaprospectivecohortstudy
AT namhyunwoo automateddetectionofsleepapneahypopneaeventsbasedon60ghzfrequencymodulatedcontinuouswaveradarusingconvolutionalrecurrentneuralnetworksapreliminaryreportofaprospectivecohortstudy
AT leejihyun automateddetectionofsleepapneahypopneaeventsbasedon60ghzfrequencymodulatedcontinuouswaveradarusingconvolutionalrecurrentneuralnetworksapreliminaryreportofaprospectivecohortstudy
AT kimhyojin automateddetectionofsleepapneahypopneaeventsbasedon60ghzfrequencymodulatedcontinuouswaveradarusingconvolutionalrecurrentneuralnetworksapreliminaryreportofaprospectivecohortstudy
AT hongseungno automateddetectionofsleepapneahypopneaeventsbasedon60ghzfrequencymodulatedcontinuouswaveradarusingconvolutionalrecurrentneuralnetworksapreliminaryreportofaprospectivecohortstudy
AT janggwangsoo automateddetectionofsleepapneahypopneaeventsbasedon60ghzfrequencymodulatedcontinuouswaveradarusingconvolutionalrecurrentneuralnetworksapreliminaryreportofaprospectivecohortstudy
AT limsungmook automateddetectionofsleepapneahypopneaeventsbasedon60ghzfrequencymodulatedcontinuouswaveradarusingconvolutionalrecurrentneuralnetworksapreliminaryreportofaprospectivecohortstudy
AT kimbaekhyun automateddetectionofsleepapneahypopneaeventsbasedon60ghzfrequencymodulatedcontinuouswaveradarusingconvolutionalrecurrentneuralnetworksapreliminaryreportofaprospectivecohortstudy