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The Role of FOXP3 on Tumor Metastasis and Its Interaction with Traditional Chinese Medicine

Forkhead box protein 3 (FOXP3) is an important transcription factor for regulatory T cells (Tregs) and plays an important role in their immunosuppressive function. In recent years, studies have found that FOXP3 is expressed in many kinds of tumors and plays different roles in tumors’ biological beha...

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Autores principales: Ma, Benxu, Miao, Wenjun, Xiao, Jieqiong, Chen, Xinyi, Xu, Jing, Li, Yinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570879/
https://www.ncbi.nlm.nih.gov/pubmed/36235242
http://dx.doi.org/10.3390/molecules27196706
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author Ma, Benxu
Miao, Wenjun
Xiao, Jieqiong
Chen, Xinyi
Xu, Jing
Li, Yinan
author_facet Ma, Benxu
Miao, Wenjun
Xiao, Jieqiong
Chen, Xinyi
Xu, Jing
Li, Yinan
author_sort Ma, Benxu
collection PubMed
description Forkhead box protein 3 (FOXP3) is an important transcription factor for regulatory T cells (Tregs) and plays an important role in their immunosuppressive function. In recent years, studies have found that FOXP3 is expressed in many kinds of tumors and plays different roles in tumors’ biological behaviors, including tumor proliferation, metastasis, drug resistance, and prognosis. However, the effects of FOXP3 on tumor metastasis and its interaction with traditional Chinese medicine (TCM) remain unclear. Therefore, in this review, we focus on the effects of FOXP3 on tumor metastasis and its relationship with TCM, which can provide evidence for further research and therapy in clinical settings.
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spelling pubmed-95708792022-10-17 The Role of FOXP3 on Tumor Metastasis and Its Interaction with Traditional Chinese Medicine Ma, Benxu Miao, Wenjun Xiao, Jieqiong Chen, Xinyi Xu, Jing Li, Yinan Molecules Review Forkhead box protein 3 (FOXP3) is an important transcription factor for regulatory T cells (Tregs) and plays an important role in their immunosuppressive function. In recent years, studies have found that FOXP3 is expressed in many kinds of tumors and plays different roles in tumors’ biological behaviors, including tumor proliferation, metastasis, drug resistance, and prognosis. However, the effects of FOXP3 on tumor metastasis and its interaction with traditional Chinese medicine (TCM) remain unclear. Therefore, in this review, we focus on the effects of FOXP3 on tumor metastasis and its relationship with TCM, which can provide evidence for further research and therapy in clinical settings. MDPI 2022-10-08 /pmc/articles/PMC9570879/ /pubmed/36235242 http://dx.doi.org/10.3390/molecules27196706 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ma, Benxu
Miao, Wenjun
Xiao, Jieqiong
Chen, Xinyi
Xu, Jing
Li, Yinan
The Role of FOXP3 on Tumor Metastasis and Its Interaction with Traditional Chinese Medicine
title The Role of FOXP3 on Tumor Metastasis and Its Interaction with Traditional Chinese Medicine
title_full The Role of FOXP3 on Tumor Metastasis and Its Interaction with Traditional Chinese Medicine
title_fullStr The Role of FOXP3 on Tumor Metastasis and Its Interaction with Traditional Chinese Medicine
title_full_unstemmed The Role of FOXP3 on Tumor Metastasis and Its Interaction with Traditional Chinese Medicine
title_short The Role of FOXP3 on Tumor Metastasis and Its Interaction with Traditional Chinese Medicine
title_sort role of foxp3 on tumor metastasis and its interaction with traditional chinese medicine
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570879/
https://www.ncbi.nlm.nih.gov/pubmed/36235242
http://dx.doi.org/10.3390/molecules27196706
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