The Role of FOXP3 on Tumor Metastasis and Its Interaction with Traditional Chinese Medicine

Forkhead box protein 3 (FOXP3) is an important transcription factor for regulatory T cells (Tregs) and plays an important role in their immunosuppressive function. In recent years, studies have found that FOXP3 is expressed in many kinds of tumors and plays different roles in tumors’ biological beha...

Descripción completa

Detalles Bibliográficos
Autores principales: Ma, Benxu, Miao, Wenjun, Xiao, Jieqiong, Chen, Xinyi, Xu, Jing, Li, Yinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570879/
https://www.ncbi.nlm.nih.gov/pubmed/36235242
http://dx.doi.org/10.3390/molecules27196706
_version_ 1784810220906610688
author Ma, Benxu
Miao, Wenjun
Xiao, Jieqiong
Chen, Xinyi
Xu, Jing
Li, Yinan
author_facet Ma, Benxu
Miao, Wenjun
Xiao, Jieqiong
Chen, Xinyi
Xu, Jing
Li, Yinan
author_sort Ma, Benxu
collection PubMed
description Forkhead box protein 3 (FOXP3) is an important transcription factor for regulatory T cells (Tregs) and plays an important role in their immunosuppressive function. In recent years, studies have found that FOXP3 is expressed in many kinds of tumors and plays different roles in tumors’ biological behaviors, including tumor proliferation, metastasis, drug resistance, and prognosis. However, the effects of FOXP3 on tumor metastasis and its interaction with traditional Chinese medicine (TCM) remain unclear. Therefore, in this review, we focus on the effects of FOXP3 on tumor metastasis and its relationship with TCM, which can provide evidence for further research and therapy in clinical settings.
format Online
Article
Text
id pubmed-9570879
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-95708792022-10-17 The Role of FOXP3 on Tumor Metastasis and Its Interaction with Traditional Chinese Medicine Ma, Benxu Miao, Wenjun Xiao, Jieqiong Chen, Xinyi Xu, Jing Li, Yinan Molecules Review Forkhead box protein 3 (FOXP3) is an important transcription factor for regulatory T cells (Tregs) and plays an important role in their immunosuppressive function. In recent years, studies have found that FOXP3 is expressed in many kinds of tumors and plays different roles in tumors’ biological behaviors, including tumor proliferation, metastasis, drug resistance, and prognosis. However, the effects of FOXP3 on tumor metastasis and its interaction with traditional Chinese medicine (TCM) remain unclear. Therefore, in this review, we focus on the effects of FOXP3 on tumor metastasis and its relationship with TCM, which can provide evidence for further research and therapy in clinical settings. MDPI 2022-10-08 /pmc/articles/PMC9570879/ /pubmed/36235242 http://dx.doi.org/10.3390/molecules27196706 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Ma, Benxu
Miao, Wenjun
Xiao, Jieqiong
Chen, Xinyi
Xu, Jing
Li, Yinan
The Role of FOXP3 on Tumor Metastasis and Its Interaction with Traditional Chinese Medicine
title The Role of FOXP3 on Tumor Metastasis and Its Interaction with Traditional Chinese Medicine
title_full The Role of FOXP3 on Tumor Metastasis and Its Interaction with Traditional Chinese Medicine
title_fullStr The Role of FOXP3 on Tumor Metastasis and Its Interaction with Traditional Chinese Medicine
title_full_unstemmed The Role of FOXP3 on Tumor Metastasis and Its Interaction with Traditional Chinese Medicine
title_short The Role of FOXP3 on Tumor Metastasis and Its Interaction with Traditional Chinese Medicine
title_sort role of foxp3 on tumor metastasis and its interaction with traditional chinese medicine
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9570879/
https://www.ncbi.nlm.nih.gov/pubmed/36235242
http://dx.doi.org/10.3390/molecules27196706
work_keys_str_mv AT mabenxu theroleoffoxp3ontumormetastasisanditsinteractionwithtraditionalchinesemedicine
AT miaowenjun theroleoffoxp3ontumormetastasisanditsinteractionwithtraditionalchinesemedicine
AT xiaojieqiong theroleoffoxp3ontumormetastasisanditsinteractionwithtraditionalchinesemedicine
AT chenxinyi theroleoffoxp3ontumormetastasisanditsinteractionwithtraditionalchinesemedicine
AT xujing theroleoffoxp3ontumormetastasisanditsinteractionwithtraditionalchinesemedicine
AT liyinan theroleoffoxp3ontumormetastasisanditsinteractionwithtraditionalchinesemedicine
AT mabenxu roleoffoxp3ontumormetastasisanditsinteractionwithtraditionalchinesemedicine
AT miaowenjun roleoffoxp3ontumormetastasisanditsinteractionwithtraditionalchinesemedicine
AT xiaojieqiong roleoffoxp3ontumormetastasisanditsinteractionwithtraditionalchinesemedicine
AT chenxinyi roleoffoxp3ontumormetastasisanditsinteractionwithtraditionalchinesemedicine
AT xujing roleoffoxp3ontumormetastasisanditsinteractionwithtraditionalchinesemedicine
AT liyinan roleoffoxp3ontumormetastasisanditsinteractionwithtraditionalchinesemedicine

Ejemplares similares